Herpes zoster, or shingles, is caused by reactivation of varicella zoster virus, which causes chickenpox. There are an estimated 1 million cases in the Unites States annually, with an individual lifetime risk of 30%. Patients with conditions that decrease cell-mediated immunity are 20 to 100 times more likely to develop herpes zoster. Patients may present with malaise, headache, low-grade fever...

PURPOSE To determine the incidence of Herpes zoster in patients with one of 17 specific underlying diseases compared with that in patients with other underlying diseases. METHODS We conducted a retrospective hospital-based cohort study using data from patients' electronic medical records for the period 2001-2007 of the Kitano Hospital Research Database. These analyses included 55,492 patients...

BACKGROUND Herpes zoster is an important problem of public health especially among the elderly in Spain. METHODS A population-based retrospective epidemiological study to estimate the burden of herpes zoster requiring hospitalization in the Canary Islands, Spain was conducted by using data from the national surveillance system for hospital data, Conjunto Mínimo Básico de Datos. Records of all...

BACKGROUND Little is known concerning risk factors for herpes zoster in the general population. We hypothesised that inhaled corticosteroids (ICS) are a risk factor for herpes zoster especially among users of inhibitors of cytochrome P450 enzymes involved in their metabolism. METHODS We identified a cohort of adult users of respiratory medications in the General Practice Research Database and...

1. Straus SE, Ostrove JM, Inchauspe G et al. NIH conference. Varicellazoster virus infections. Biology, natural history, treatment, and prevention. Ann Intern Med 1988; 108: 221–237 2. Schmader K. Herpes zoster in older adults. Clin Infect Dis 2001; 32: 1481–1486 3. Buchbinder SP, Katz MH, Hessol NA et al. Herpes zoster and human immunodeficiency virus infection. J Infect Dis 1992; 166: 1153–11...

BACKGROUND As general anaesthesia may compromise the immune system, it has been hypothesized that latent varicella-zoster virus is more likely to be reactivated and cause herpes zoster in mothers after Caesarean deliveries under general anaesthesia. Our study was thus aimed at investigating the risk of herpes zoster among women during the first year after Caesarean deliveries under either gener...

Ganglia obtained at autopsy were examined by in situ hybridization from one patient with zoster (also called herpes zoster or shingles), two varicella-zoster virus (VZV)-seropositive patients with clinical evidence of zoster, one VZV-seronegative child, and one fetus. Ganglia positive for VZV had a hybridization signal in both neuronal and nonneuronal satellite cells. Ganglia obtained from the ...

Edema bullae typically forms at the site of skin swelling during acute states of volume overload, most commonly during renal or cardiac failure. Herpes zoster is a reactivation of latent varicella zoster virus that typically presents as painful vesicles in a dermatomal distribution. In immunocompromised individuals, disseminated herpes zoster skin manifestations may occur with several lesions i...

Herpes zoster (shingles) is rare in children with no history of chickenpox but can occur when their mothers are infected with the virus during pregnancy. In such cases, herpes zoster generally presents after the first year of life after maternal immunoglobulin (Ig) G antibodies have disappeared from the child’s blood. Disseminated pediatric herpes zoster is an unusual condition. We present the ...

INTRODUCTION Simultaneous involvements of multiple cranial nerve ganglia (geniculate ganglion and peripheral ganglia of cranial nerves VIII, IX and X) by varicella-zoster virus and its subsequent activation may result in the characteristic eruptions of herpes zoster cephalicus. Coexistence of facial palsy and involvement of upper cervical dermatomes by varicella-zoster virus is quite rare. CA...