objective: β-thalassemia is caused by absence or reduction of β-globin chain synthesis. one of the effective therapeutic methods for this disease can be gene therapy by viral vectors. the capacity of lentiviral vectors is approximately 8 kb, we designed a 6 kb construct containing mini lcr and β-globin gene instead of lcr region. the aim of this study is to make a recombinant lentiviruses conta...

This method paper addresses an untapped but important type of IT turnover: IT entrepreneurship. We seek to develop a mixed methods research (MMR) design to understand the factors and processes that influence turnover behavior of prospective (nascent) IT entrepreneurs. To do this, we review two prior streams of research: the entrepreneurship literature and IT employee turnover. We incorporate th...

I have recently started university and moved away from home, and also I have met a guy who is now my boyfriend; it is going to be three weeks since we started dating and it has all been really good. We also have already started talking about making love and my boyfriend isn't forcing me into anything, and when I'm with him, it feels right, but the only thing that is bothering me is the fact it ...

The reaction of (F3C)Cl2SiCl3 with the lithiated hydrazine LiN(Me)NMe2 gives the compound (F3C)Cl2SiN(Me)NMe2 (1) and in traces Cl3SiN(Me)NMe2 (2). The reactions with LiN(SiMe3)NMe2 and LiONMe2 give (F3C)Cl2SiN(SiMe3)NMe2 (4) and (F3C)Cl2SiONMe2 (5), respectively. The compounds were characterised by multinuclear solution NMR, gas-phase IR spectroscopy and mass spectrometry. Information about co...

The animal world is replete with vibrant colours: these are often used as display signals and selection has solved a fundamental problem in information transfer by enhancing the detectability of these signals against the backgrounds on which they are perceived by the particular sensory systems of their receivers.

We consider the ω1-Borel subsets of the reals in models of ZFC. This is the smallest family of sets containing the open subsets of the 2 and closed under ω1 intersections and ω1 unions. We show that Martin’s Axiom implies that the hierarchy of ω1-Borel sets has length ω2. We prove that in the Cohen real model the length of this hierarchy is at least ω1 but no more than ω1 + 1. Some authors have...

Understanding social cognition has become a hallmark in deciphering autism spectrum disorder. Neurobiological theories are taking precedence in causation studies as researchers look to abnormalities in brain development as the cause of deficits in social behavior, cognitive processes, and language. Following their discovery in the 1990s, mirror neurons have become a dominant theory for that the...

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