Warm mix asphalts (WMA), because of their low production and compact temperatures, may have different behaviors in long term. In the present work, the energy-based criteria along with the 50% reduction in initial stiffness (Nf50%) using four-point bending test under controlled-strain conditions of 1000 microstrain were applied to compare the prepared two warm mix and HMA samples. All these crit...

Reclaimed asphalt pavement (RAP) is one of the waste materials that highway agencies promote to use in new construction or rehabilitation of highways pavement. Since the use of RAP can affect the resilient modulus and other structural properties of flexible pavement layers, this paper aims to employ two different artificial neural network (ANN) models for modeling and evaluating the effects of ...

Introduction: Diarrheagenic Escherichia coli (DEC) including enteropathogenic (EPEC), enteroaggregative (EAEC), enterotoxigenic (ETEC), and shiga toxin producing E. coli are among the most common agents of diarrhea. There are various classes of iron uptake receptors, but there is not much data on the presence of these iron receptors in DEC isolates. The present study aimed to evaluate the prese...

The hypomethylating agents (HMA) azacitidine (AZA) and decitabine (DAC) are active in Chronic Myelomonocytic Leukemia (CMML) with overall response rates (ORR) of 40–70%, translating into median overall survivals (OS) of 12–22 months. Response to HMA in these CMML cohorts was mostly evaluated according to IWG-2006 criteria, which do not assess improvement of myeloproliferative features nor quali...

BACKGROUND A sensitive gas chromatography-mass spectrometry method was developed and validated for the simultaneous measurement of MDEA, MDMA, and its metabolites, 3,4-methylenedioxy-N-ethylamphetamine (MDEA), 3,4-methylenedioxymethamphetamine (MDMA or Ecstasy), and its metabolites, 4-hydroxy-3-methoxyamphetamine (HMA), 3,4-methylenedioxyamphetamine (MDA), and 4-hydroxy-3-methoxyamphetamine (HM...

In this study, we have investigated the diversity of current HIV-1 strains circulating in the metropolitan area of Lisbon, Portugal. A total of 217 HIV-1-positive blood samples, collected between October 1998 and December 2000, was genetically characterized in the gp120 C2V3C3 region (n = 205) or part of the gp41 N-terminal segment (n = 12) by heteroduplex mobility assay (HMA) and/or DNA sequen...

Specific phenotypic subpopulations of cancer stem cells (CSCs) are responsible for tumor development, production of heterogeneous differentiated tumor mass, metastasis, and resistance to therapies. The development of therapeutic approaches based on targeting rare CSCs has been limited partially due to the lack of appropriate experimental models and measurement approaches. The current study pres...