Objective: Asafoetida (Ferula assa-foetida) is known as a valuable remedy for whooping cough, pneumonia, bronchitis in children and asthma treatment in folk medicine. In the present study the relaxant effects of the asafoetida on tracheal smooth muscle of guinea pigs and its probable mechanism(s) were examined. Materials and Methods: The relaxant effects of three cumulative concentrations of th...

BACKGROUND The prevalence of Diabetes mellitus (DM) is escalating rapidly worldwide, and associated with micro- and macrovascular complications. Diabetic neuropathy (DN) is a common complication of DM, and has a few approved therapies with limited efficacy and several side-effects. Herbal medicine is used worldwide as an effective alternative-medicine. The present study aims to investigate the ...

This study was conducted at the animal production department, College of Agriculture Engineering Sciences , University Duhok, in order to investigate effect ration replacement with ferula on productive performance and some physiological parameters quail. Three hundred sixty day old quail birds were divided into four groups three replicates group (30 replicate, treated from age 7days till 42days...

Effect of hexane extract of Ferula jaeschkeana has been studied on corpora lutea of adult cyclic guinea-pigs. Administration of extract showed duration dependent luteolytic changes in the corpora lutea. Its administration for first three days from the onset of estrus caused significant decrease in the diameter of corpora lutea in the ovary at day 10 of cycle. Ovarian wet weight, proteins and gl...

The present study explores the hepatoprotective activity of various extracts of Ferula asafoetida, Momordica charantia Linn and Nardostachys jatamansi against experimental hepatotoxicity. Polyherbal suspensions were formulated using extracts showing significant activity and evaluated for both physicochemical and hepatoprotective activity in comparison with LIV-52 as standard. Petroleum ether (6...

chemical composition of the essential oil of the fruit of ferula assafoetida l. obtained by steam distillation solvent extraction methodhas been studied by gc/ms for the first time. fifty-four components, comprising 96.9% of the total oil, were identified.epi-α-cadinol (23.15 %), germacrene b (10.98 %), α-gurjunene (6.18 %), (z)-1-propenyl secbutyl disulfide (5.89 %), 5-epi-7-epi-α-eudesmol (4....

Background and objectives: Interaction of compounds with ct-DNA can affect the replication, protein synthesis and cell division. Different species of the genus Ferula (Apiaceae) have shown various biomedical applications for many centuries. Biological features of this genus such as cytotoxicity, antibacterial, antiviral, P-glycoprotein (P-gp) inhibitory and antiinflamm...