A robust and rapid analysis method was developed and validated for the simultaneous assay of paclitaxel (PTX) and lapatinib (LPT) in a polymeric micelle formulation as a novel drug delivery system using high-performance liquid chromatography (HPLC). The assay was performed using the C18 MZ-Analytical Column (5 μm, 150 × 4.6 mm, OSD-3) which was protected with the C18 pre-column (5 μm, 4.0 × 4.6...

Early experiences with offshore software development (OSD) have not been consistently positive. There have been abundant media reports of various companies whose offshore projects were not able to live up to expectations. It would appear that this can be traced back to insufficient project management by the offshore project partners. In this context, some research has been carried out on the cr...

The satellite symposium ‘Role of Preservative-free Therapies in the Treatment of Glaucoma’ at the 2013 annual meeting of the European Society of Ophthalmology in Copenhagen included presentations from four leaders in the field of glaucoma treatment. The first of these stressed that among patients with glaucoma, 20–30 % have severe ocular surface disease (OSD). The risk of OSD is significantly i...

Corynebacterium pseudotuberculosis is a Gram-positive, pleomorphic, facultative intracellular pathogen that causes Oedematous Skin Disease (OSD) in buffalo. To better understand the pathogenic mechanisms of OSD, we performed a comparative genomic analysis of 11 strains of C. pseudotuberculosis isolated from different buffalo found to be infected in Egypt during an outbreak that occurred in 2008...

Introduction The purpose of this paper was to evaluate and compare the questionnaires regarding sleep quality among children aged up to 12 years old, used in the Portuguese language in Brazil. Material and methods A search at the literature databases of Lilacs, Scielo and Pubmed was performed using keywords "sleep quality" and "children". Selected Articles were analysed for age of the studied...

The toxicity of spill-treating agents (STAs) is a topic that needs to be assessed prior to their potential application in environmental disasters. The aim of the present work was to study the effects of four commercial STAs (CytoSol, Finasol OSR 51, Agma OSD 569 and OD4000) on the growth of marine (Phaeobacter sp., Pseudomonas sp.) and terrestrial (Leuconostoc mesenteroides) bacteria, and sea u...

There is an urgent need in a wide range of fields such as logistics and supply chain management to develop effective approaches to measure and/or optimally design a network system comprised of a set of units. Data envelopment analysis (DEA) researchers have been developing network DEA models to measure decision making units’ (DMUs’) network systems. However, to our knowledge, there are no previ...

Osgood-Schlatter disease (OSD) is a condition in which the patellar tendon insertion on the tibial tuberosity becomes inflamed. It is a well-known condition in late childhood characterized by pain and a bony prominence over the tibial tuberosity. The pain is usually exacerbated by physical activities like running, jumping, and climbing stairs. In the acute stage, the margins of the patellar ten...