Developing new bone pain palliation agents is a mandate in handling end-stage cancer patients around the world. Possibly, Lu-177 ethylenediaminetetramethylene phosphonic acid (177Lu-EDTMP) is a therapeutic agent which can be widely used in bone palliation therapy. In this study, 177Lu-EDTMP complex was prepared successfully using synthesized EDTMP ligand and 177LuCl3. Lu-177 chloride was obt...

UNLABELLED One mechanism of resistance to trastuzumab in human epidermal growth factor receptor-2 (HER2)-positive breast cancer (BC) is increased epidermal growth factor receptor (EGFR) expression. We have developed (111)In-labeled bispecific radioimmunoconjugates (bsRICs) that bind HER2 and EGFR on BC cells by linking trastuzumab Fab fragments through a polyethylene glycol (PEG24) spacer to ep...

In the present paper, by considering the notion of MV-modules which is the structure that naturally correspond to lu-modules over lu-rings, we prove some results on prime A-ideals and state some conditions to obtain a prime A-ideal in MV-modules. Also, we state some conditions that an A-ideal is not prime and investigate conditions that $Ksubseteq bigcup _{i=1}^{n}K_{i}$ implies $Ksubseteq K_{j...

The coordination properties of the ligand 2,2'-bipyrimidine-4,4'-dicarboxylic acid (H2bpd) with lanthanide(III) ions (Ln = Eu, Tb, or Lu) were investigated. syntheses H2bpd and its salts, [K2(bpd)(H2O)2] (1) [(AlkNH)Lu(bpd)2] (Alk Et, Hex, en), are described. In presence LnCl3 salts Lu, Tb), formation [Ln(bpd)2]- [Ln(bpd)(H2O)x]+ species was assessed by 1H nuclear magnetic resonance (NMR), spec...