The aim of this study was to clarify whether myocardial cells with DNA fragmentation induced by ischemia show increased plasma-membrane permeability (PMP), focusing on the early lesions of acute myocardial ischemia (AMI). Rat AMI was induced by a permanent occlusion of the left coronary artery. The TUNEL method was used for the demonstration of DNA fragmentation, and lanthanum ions (La) were em...

Pulsed Melodic Processing (PMP) is a computation protocol that utilizes musically-based pulse sets (“melodies”) for processing – capable of representing the arousal and valence of affective states. Affective processing and affective input/output are key tools in artificial intelligence and computing. In the designing of processing elements (e.g. bits, bytes, floats, etc.), engineers have primar...

Current technology for penile hemodynamic evaluations in small animals is invasive and has limitations. We evaluated a novel laser speckle contrast imaging (LSCI) technique to determine age-related changes in penile microvascular perfusion (PMP) and tested the role of cavernosal muscle (CC) fibrosis mediated by Wnt-TGF β1 signaling pathways in a mouse model. Ten young (2-3 months) and old (24-2...

Auditing tools can play a key role in the continuous improvement of maintenance policies, in particular to enhance predictive maintenance (PM). This paper proposes a multi-criteria model for auditing a Predictive Maintenance Programme (PMP) developed and implemented in the General Hospital of Ciudad Real (GHCR) in Spain. The model has a two-level structure, with top level auditing areas specifi...

We determined the provision for dialysis treatment in Malaysia. There were 181 dialysis centres as at 1st June 1999 (161 Haemodialysis (HD) and 20 Continuous Ambulatory Peritoneal Dialysis (CAPD) centres), providing treatment for 5614 patients. This is equivalent to an estimated prevalence rate of 253 patients per million population (pmp) and new dialysis acceptance rate of 49 patients pmp. Dia...

OBJECTIVE To develop a flow cytometric assay to quantify platelet-derived microparticles (PMPs) in equine whole blood and plasma. SAMPLE Citrate-anticoagulated whole blood from 30 healthy adult horses. PROCEDURES Platelet-poor plasma (PPP) was prepared from fresh whole blood by sequential low-speed centrifugation (twice at 2,500 × g). Samples of fresh whole blood and PPP were removed and st...

Tyrosine phosphorylation is a common protein post-translational modification that plays a critical role in signal transduction and the regulation of many cellular processes. Using a propeptide strategy to increase cellular uptake of O-phosphotyrosine (pTyr) and its nonhydrolyzable analog 4-phosphomethyl-L-phenylalanine (Pmp), we identified an orthogonal aminoacyl-tRNA synthetase-tRNA pair that ...

This paper reviews and discusses the more recent literature and application of Positive Mathematical Programming in the context of agricultural supply models. Specifically, advances in the empirical foundation of parameter specifications as well as the economic rationalisation of PMP models – both criticized in earlier reviews – are investigated. Moreover, the paper provides an overview on a la...

INTRODUCTION Tuberculosis (TB) requires at least six months of multidrug treatment and necessitates monitoring for response to treatment. Historically, public health departments (HDs) have cared for most TB patients in the United States. The Affordable Care Act (ACA) provides coverage for uninsured persons and may increase the proportion of TB patients cared for by private medical providers and...

The Natural Resources Conservation Service (NRCS) has assisted local sponsors with analysis, design and construction of approximately 26,000 of the 80,000 dams in the National Inventory of Dams. Many of these dams are reaching their design life and require rehabilitation. Rehabilitation efforts come at a time when NRCS is in the process of evaluating a potential change from a minimum 6-hour sto...