The UT-A1 and UT-A3 urea transporters are expressed in the terminal inner medullary collecting duct (IMCD) and play an important role in the production of concentrated urine. We showed that both hyperosmolarity and vasopressin increase urea permeability in perfused rat terminal IMCDs and that UT-A1 and UT-A3 accumulate in the plasma membrane in response to vasopressin. In this study, we investi...

We previously reported results of a phase II trial in which recombinant MAGE-A3 protein was administered with or without adjuvant AS02B to 18 non-small-cell lung cancer (NSCLC) patients after tumor resection. We found that the presence of adjuvant was essential for the development of humoral and cellular responses against selected MAGE-A3 epitopes. In our current study, 14 patients that still h...

تێکەلبوونا ژانرێن ئەدەبى مەبەست ژێ نەمانا سنورانە دناڤبەرا ئەدەبیدا کو نڤیسەر و رەخنەگر وەسا سەردەریێ ل گەل تێکستى دکەن چ چارچوڤەیێن دەستنیشانکرى نین، ژێر ناڤێ بیت، یان هەڤتێکستییێ لەورا چیرۆک ژى وەک ژانرەکێ پەخشانى ئەڤ دیاردا دناڤدا دهێتە دیتن. گریمانا ئەڤێ ڤەکولینێ ئەوە ژانرێ شیعرى د چیرۆکێن گوڤارا "پەیڤ"دا (1993-2003)، خزمەتا چیرۆکێ دابووینە نە، ب شێوەیەکێ هەرەمەکى خو دناڤ ئەوان تێکستێن چیرۆ...

Annexin A3 has been identified as a novel biomarker in different types of cancers. However, little is known about its clinical significances and and biological roles in gastric cancer. In this study, we assessed annexin A3 expression in 80 patients with gastric cancer and explore its correlation with prognosis Moreover, correlations with Ki-67, Bcl-2 and Bax were also investigated. Expression o...

Objective: To construct and identify recombinant expression of a therapeutic tumor vaccine with HBcAg as a vector. Methods: PCR primers were designed according to the gene sequences of restriction enzyme sites of recombinant pKK233.2-hepatitis B core antigen (HBcAg) and melanoma-associated antigen 3 (MAGE-A3: 112120aa). The target fragment of MAGE-A3 was synthesized and cloned to pKK233.2-HBcAg...

Let A3 be the set of all positive integers pqr, where p, q, r are primes and possibly two, but not all three of them are equal. For any n = pqr ∈ A3, define a function w by w(n) = P (p + q)P (p + r)P (q + r), where P (m) is the largest prime factor of m. It is clear that if n = pqr ∈ A3, then w(n) ∈ A3. For any n ∈ A3, define w0(n) = n, wi(n) = w(wi−1(n)) for i = 1, 2, . . . . An element n ∈ A3...

i=1 Ai \⋃ k 6=i Ak  , {∑10 j=1 1Aj = 1} . (b) Setting A1 := B, A2 = A \ B and A3 = A, we see that Aj, j = 1, 2, 3, form a partition of Ω. The σ-algebra generated by the partition consists of all possible unions of its elements: σ({A,B}) = σ({A1, A3, A3}) = {∅, A1, A2, A3, A1 ∪ A2, A1 ∪ A3, A2 ∪ A3,Ω}. (c) No, F is not a σ-algebra, as the second axiom (A.2) fails: (B1 ×B2) doesn’t have the sp...

Epithelial ovarian cancer (EOC) is the leading cause of death among gynecological malignancies and is rarely cured in the recurrent setting, mainly because of progressive chemoresistance, especially platinum resistance. In our previous studies, the platinum-resistance-related protein, annexin A3, was selected by comparative proteomics. In this study, we detected serum annexin A3 levels using a ...

Using elementary means, we derive an explicit formula for a3(n), the number of 3-core partitions of n, in terms of the prime factorization of 3n + 1. Based on this result, we are able to prove several infinite families of arithmetic results involving a3(n), one of which specializes to the recent result of Baruah and Berndt which states that, for all n ≥ 0, a3(4n + 1)= a3(n). 2000 Mathematics su...