Background: The main characteristic of polycystic ovary syndrome (PCOS) is oligomenorrhea with clinical and biochemical signs of hyperandrogenism(HA) and the phenotypic spectrum of PCOS is very broad. There are very limited studies about the features of patients with PCOS in Iran. The purpose of this study is to compare the clinical and laboratory characteristics of PCOS between the overweight ...

Background: Imatinib mesylate (IM), a strong and selective tyrosine kinase inhibitor, has been approved as the front line of treatment in chronic myeloid leukemia (CML) patients. In spite of satisfactory results of imatinib in the treatment of patients with CML, patients with treatment failure or suboptimal response developed resistance that might be because of pharmacogenetic variants. This st...

The latest neuroimaging studies about implicit memory (IM) have revealed that different IM types may be processed by different parts of the brain. However, studies have rarely examined what subtypes of IM processes are affected in patients with various brain injuries. Twenty patients with frontal lobe injury, 25 patients with occipital lobe injury, and 29 healthy controls (HC) were recruited fo...

Während in der Vergangenheit der IT-Einsatz im kaufmännischen Bereich im Vordergrund stand, wird durch die verstärkten Bemühungen zur Kostensenkung, Effizienzund Qualitätssteigerung im Gesundheitswesen auch der medizinische Bereich im Krankenhaus immer stärker von IT-Systemen durchdrungen [1]. Angesichts der Einführung eines pauschalierten Entgeltsystems (DRGs) zum 01.01.2004 für die Abrechnung...

We conceptualize two distinct post-acceptance usage behaviors: (1) routine use (RTN) refers to the use of information system (IS) consistent with normal work processes and (2) innovative use (INV) means users’ applying system features in novel ways. While RTN helps integrate the implemented IS into work processes, INV further extracts the value of the IS. Drawing on motivation theory, we propos...

Nach den terroristischen Anschlägen in Paris 2015 und Brüssel 2016 wurde das Bedürfnis nach mehr Sicherheit und Überwachung im Internet laut. Als Folge der Enthüllungen der Überwachungsund Spionagetechniken der National Security Agency (NSA) durch Edward Snowden 2013 konnte in der Bevölkerung aber auch ein Aufschrei nach erhöhtem Schutz der Privatsphäre im Internet wahrgenommen werden. Die gesc...

The present study examined whether the central bottleneck, assumed to be primarily responsible for the psychological refractory period (PRP) effect, is intact, bypassed, or shifted in locus with ideomotor (IM)-compatible tasks. In 4 experiments, factorial combinations of IM- and non-IM-compatible tasks were used for Task 1 and Task 2. All experiments showed substantial PRP effects, with a stron...

Possible Lines of Approach • Representative status of IM for the Victorian era, poet laureateship • IM and the culture of mourning, public and private, mourning process, melancholia • Form and structure of IM, composition over 17 years, issue of unity vs. division • Poetics: tetrameter, abba rhyme scheme, repetition, use of apostrophe • Comparison with other elegies (e.g. Milton’s “Lycidas,” Sh...

Seven compounds with framework structures made of divalent metal-imidazole (Im) complexes (M(II) = Co, Ni, and Mn) linked by 1,5-napthalenedisulfonate (1,5nds) were synthesized and structurally characterized. Five of these compounds, Mn(Im)(4)(1,5nds) (two forms), Co(Im)(4)(1,5nds) (two forms), and Ni(Im)(4)(1,5nds), contain direct sulfonate-metal coordination and represent the first such compo...

BACKGROUND AND OBJECTIVES Imatinib mesylate (IM) is the choice treatment for Bcr/Abl-positive malignancies. Emergence of resistance to IM warrants the exploration of novel well-tolerated anticancer agents. We intended to evaluate the effect of PS-341 on proliferation, survival, and cellular events in Bcr/Abl-positive cells sensitive and resistant to IM, and to investigate the effect of PS-341 a...