AIM The aim was to evaluate the analgesic, anti-inflammatory, and anti-hyperlipidemic activities of Commiphora molmol extract (CME) and its effects on body weight and blood lipids. MATERIALS AND METHODS The analgesic effect was assessed using thermal (hot plate test) and chemical (writhing test) stimuli to induce central and peripheral pain in mice. The anti-inflammatory activity was determin...

OBJECTIVE The present study was undertaken to evaluate the possible analgesic, neuropharmacological, anti-diarrheal, and cytotoxic activities of the ethanol extract of leaves of Solanum sisymbriifolium Lam. (Family: Solanaceae). MATERIALS AND METHODS The analgesic activity was measured by acetic acid-induced writhing inhibition test. The neuropharmacological activities were evaluated using ho...

background: herbal medical compounds and their major constituent have been used in the management and treatment of opioid withdrawal syndrome and pain. this study was carried out to clarify the effect of curcumin, the major compound of turmeric, on morphine withdrawal syndrome in mouse model and its possible mechanisms of pain relieving activity by assessing in writhing test as a model of visce...

D-002, a mixture of six higher aliphatic alcohols purified from beeswax, has been shown to produce anti-inflammatory effects in experimental models, devoid of gastrotoxic or hepatotoxic effects. Some studies have demonstrated that D-002 exerts analgesic effects, but just related to its anti-inflammatory action. The objective of this study was to compare the effects of D-002, naproxen, aspirin a...

Calendula Of.cinalis (Asteraceae) is widely used in traditional medicine as an anti-in.ammatory agent and has also been reported to have anti-bacterial, anti-fungal and anti-viral activities.  Sesquiterpene glycosides, saponins, triol, triterpenes and .avonoids are observed in its composition. The present study was designed to evaluate the antinociceptive effect of hydro-alcoholic extract of Ca...

Background: Herbal medical compounds and their major constituent have been used in the management and treatment of opioid withdrawal syndrome and pain. This study was carried out to clarify the effect of curcumin, the major compound of turmeric, on morphine withdrawal syndrome in mouse model and its possible mechanisms of pain relieving activity by assessing in writhing test as a model of visce...

Abstract Background Macropanax dispermus is traditionally used to treat various diseases by ethnic people. The present research reports the pharmacological properties with phytochemical profiling of crude extracts M. leaves (MDML), its n-hexane (MDHL), carbon tetrachloride (MDTL), chloroform (MDCL), ethyl acetate (MDEL), and aqueous (MDAL) fractions, methanol stem barks (MDMS). in vitro thrombo...