We compared self-reported handicap (Hearing Handicap Inventory for the Elderly, HHIE) scores before and after a 6-week period of hearing aid use in subjects drawn from a pool of 115 elderly persons with hearing impairment. Study patients (PTs) were divided into two categories according to whether scores on a dichotic listening test (Dichotic Sentence Identification Test, DSI) were normal or abn...

BACKGROUND Young patients with obstructive sleep apnea syndrome (OSAS) display an attenuated heart rate recovery (HRR) during the first minute (HRR-1) and the first 2 min (HRR-2) postexercise. We sought to compare determinants of HRR-1 and HRR-2 in OSAS and to assess whether these associations depend on age. METHODS Exercise testing with measurements of HRR-1 and HRR-2 was performed in 54 pat...

Background: Although Daily Sedation Interruption (DSI) is associated with better physical outcomes, many intensive care (ICU) survivors continue to suffer from cognitive impairment in and beyond ICU; neither has the meaning patients attach to the experience of cognitive impairment been extensively explored in the context of DSI. Objective: To gain an understanding of and uncover the experience ...

We aimed to determine the associations between dietary sodium intake (DSI), potassium (DPI), ratio of DSI/DPI and prevalent kidney stone disease defined as self-report any previous episode stone.

Enhancement of presynaptic Ca(2+) signals is widely recognized as a potential mechanism for heterosynaptic potentiation of neurotransmitter release. Here we show that stimulation of a serotonergic interneuron increased spike-evoked Ca(2+) in a manner consistent with its neuromodulatory effect on synaptic transmission. In the gastropod mollusk, Tritonia diomedea, stimulation of a serotonergic do...

We recorded action potential activity from the isolated brain of the nudibranch seaslug Tritonia diomedea during fictive swimming. Candidate central pattern generator (CPG) interneurons were identified by their bursting patterns and positions in the brain. Previously identifed populations of interneurons were imaged, including the dorsal swim interneurons (DSI), C2, and ventral swim interneuron...

Enhancement of presynaptic Ca signals is widely recognized as a potential mechanism for heterosynaptic potentiation of neurotransmitter release. Here, we show that stimulation of a serotonergic interneuron increased spike-evoked Ca in a manner consistent with its neuromodulatory effect on synaptic transmission. In the gastropod mollusc, Tritonia diomedea, stimulation of a serotonergic dorsal sw...

Direct sample introduction (DSI), or "dirty sample injection," was investigated in the determination of 22 diverse pesticide residues in mixed apple, green bean, and carrot extracts by benchtop gas chromatography/tandem mass spectrometry (DSI/GC/MS-MS). The targeted pesticides, some of which were incurred in the samples, included chlorpyrifos, azinphos-methyl, parathion-methyl, diazinon, terbuf...

BACKGROUND Changes in myocardial microstructure are important components of the tissue response to infarction but are difficult to resolve with current imaging techniques. A novel technique, diffusion spectrum MRI tractography (DSI tractography), was thus used to image myofiber architecture in normal and infarcted myocardium. Unlike diffusion tensor imaging, DSI tractography resolves multiple m...

MRI tractography is the mapping of neural fiber pathways based on diffusion MRI of tissue diffusion anisotropy. Tractography based on diffusion tensor imaging (DTI) cannot directly image multiple fiber orientations within a single voxel. To address this limitation, diffusion spectrum MRI (DSI) and related methods were developed to image complex distributions of intravoxel fiber orientation. Her...