AIDS is a pandemic responsible for more than 35 million deaths. The emergence of resistant mutations due to drug use is the biggest cause of treatment failure. Marine organisms are sources of different molecules, some of which offer promising HIV-1 reverse transcriptase (RT) inhibitory activity, such as the diterpenes dolabelladienotriol (THD, IC50 = 16.5 µM), (6R)-6-hydroxydichotoma-3,14-diene...

This paper proposes controller design methods, specially for track-following control of the magnetic read/write head in a hard disk drive (HDD). The servo system to be considered is a general dual-stage multi-sensing system, which encompasses most of the track-following configurations encountered in the HDD industry, including the traditional single-stage system. For the general system, a robus...

Caching is an effective optimization in search engine storage architectures. Many caching algorithms have been proposed to improve retrieval performance. The data selection policy of search engine cache management plays an important role, which carefully places the data in memory or other storage, such as solid state disks (SSDs). Considering that the historical query log has a guiding role for...

Under Executive Order 12898, the U.S. Environmental Protection Agency (EPA) must perform environmental justice (EJ) reviews of its rules and regulations. EJ analyses address the hypothesis that environmental disamenities are experienced disproportionately by poor and/or minority subgroups. Such analyses typically use communities as the unit of analysis. While community-based approaches make sen...

We propose a Solid-State Disk (SSD) with a Double Data Rate (DDR) DRAM interface for high-performance PCs. Traditional SSDs simply inherit the interface protocol of Hard Disk Drives (HDD) such as Parallel Advanced Technology Attachment (PATA) or Serial-ATA (SATA) for maintaining the compatibility. However, SSD itself provides much higher performance than HDD, hence the interface also needs to b...

Web archives, query and proxy logs, and so on, can all be very large and highly repetitive; and are accessed only sporadically and partially, rather than continually and holistically. This type of data is ideal for compression-based archiving, provided that random-access to small fragments of the original data can be achieved without needing to decompress everything. The recent RLZ (relative Le...

In order to meet ambitious emission reduction goals in California, greenhouse gas emissions from direct combustion of fossil fuels for residential space and water heating will need to be largely eliminated. If those emission reductions come from fuel switching (natural gas to electricity) then the electricity grid needs to be prepared for the additional load. This paper presents a new method fo...

hydromechanical deep drawing (hdd) is one of the most convenient processes in which a sheet metal is drawn against a counter pressure rather than a rigid die in conventional stampings. this process has been increasingly used to produce aerospace and automotive components. more recently, aerospace industry is demanding new materials with capability to produce high strength to weight ratio produc...