BACKGROUND ICU care providers often feel that the care given to a patient may be inconsistent with their professional knowledge or beliefs. This study aimed to assess differences in, and reasons for, perceived inappropriate care (PIC) across ICU care providers with varying levels of decision-making power. METHODS We present subsequent analysis from the Appropricus Study, a cross-sectional stu...

Gastrointestinal epithelial barrier loss due to tight junction (TJ) dysfunction and bile acid-induced diarrhea are common in patients with inflammatory diseases. Although excess colonic bile acids are known to alter mucosal permeability, few studies have compared the effects of specific bile acids on TJ function. We report that the primary bile acid, chenodeoxycholic acid (CDCA), and its 7α-deh...

We report here the first direct measurements of persistent inward currents (PICs) in rat hindlimb motoneurons, obtained from ketamine-xylazine anesthetized rats during slow voltage ramps performed by single-electrode somatic voltage clamp. Most motoneurons expressed PICs and current-voltage (I-V) relations often contained a negative-slope region (NSR; 13/19 cells). PICs activated at -52.7 ± 3.8...

In order to enhance the charge balance of organic near infrared (NIR) electroluminescent devices, an ancillary ligand pic-SCz which was covalently linking bipolar group SCz (composed PS (S) and tBuCz (Cz)) pic (SCz=3,6-di-tert-butyl-9-(4-(phenylsulfonyl)phenyl)-9H-carbazole; = phenyl sulfone; 3,6-di-tert-butylcarbazole; pic= 2-picolinic acid) developed for iridium (III) complex (TPA-BTz-Iq)2Ir(...

a new proton transfer compound, formulated as (hamp-6-pic)(hpyzd) ∙h2o (1), has been synthesized from the reaction of pyrazine-2,3-dicarboxylic acid (h2pyzd)  and 2-amino-6-methyl pyridine (amp-6-pic), in 1:1 molar ratio. extensive o−h×××o, n−h×××n and o−h×××o hydrogen bonds involving (hamp-6-pic)+ cation, (hpyzd)- anion and co-crystal water molecule٫ static electronic٫ and π…π stacking interac...

Muon beam ionization cooling is a key component for the next generation of high-luminosity muon colliders. To reach adequately high luminosity without excessively large muon intensities, it was proposed previously to combine ionization cooling with techniques using a parametric resonance (PIC). Practical implementation of PIC proposal is a subject of this report. We show that an addition of ske...

Two types of coherent delay-locked loops (DLL) are considered in this paper as delay trackers in multiuser CDMA receivers. The rst approach is based on the parallel interference cancellation (PIC) method. PIC based delay trackers require the estimation of channel parameters and data symbols of all users to construct the multiple-access interference (MAI) estimates. The other method is based on ...

In this paper we present a wearable positioning system that requires 2.5 mA to operate. The system consists of an infrastructure of ultrasonic transmitting devices, and a receiver device on the wearable. The receiver comprises an ultrasonic pick-up, an op-amp, and a PIC. The PIC implements a particle filter for estimating X and Y positions. The transmitter layout has been chosen to simplify the...

In the parallel signal processing, the multi-user detection precision of parallel interference cancellation (PIC) detector is always easily affected by the decision error diffusion. Based on the fast convergence and low complexity of blind adaptive Kalman algorithm, a new blind adaptive Kalman-PIC (KPIC) multi-user detection (MUD) algorithm is proposed for the direct sequence spread spectrum co...

This paper describes the implementation of a PIC microcontroller in a conventional laboratory-type electronic trainer. The work comprises software for the PIC and hardware for the software. The PIC controller uses an EasyPIC-6 board and includes a PC-interfaced programmer for the PIC chip. It has many external modules: 128 × 64 graphic LCD display, 2 × 16 LCD display, 4 × 4 keypad, and port exp...