In order to bridge the gap of existing artificial heart technology to the diverse needs of the patient population, we have been investigating the viability of a scaled-down design of the current 70 cc Penn State artificial heart. The issues of clot formation and hemolysis may become magnified within a 50 cc chamber compared to the existing 70 cc one. Particle image velocimetry (PIV) was employe...

μPIV is a widely accepted tool for making accurate measurements in microscale flows. The particles that are used to seed the flow, due to their small size, undergo Brownian motion which adds a random noise component to the measurements. Brownian motion introduces an undesirable error in the velocity measurements, but also contains valuable temperature information. A PIV algorithm which detects ...

Chromatin immunoprecipitation assays were employed to assess the kinetics of transcription factor assembly and histone modifications that occur during gamma interferon (IFN-gamma) induction of CIITA gene expression. CIITA is the master regulator of major histocompatibility complex class II transcription. Promoter IV (PIV), the major IFN-gamma responsive promoter for CIITA expression, requires b...

BACKGROUND To investigate flow in the ductus venosus at 11-13 + 6 weeks of gestation in women with normal pregnancies in the Taiwanese population. METHODS Two hundred and fifty-two normal singleton pregnancies with gestational ages ranging from 11 to 13 + 6 weeks were examined in this study. The pulsatility index for veins (PIV), resistance index (RI), peak velocity during ventricular systole...

IFN-gamma induction of the CIITA (class II transactivator) promoter (pIV) requires Brahma-related gene 1 (BRG1), a chromatin-remodeling enzyme. However, the events that lead to pIV activation are only partially understood, and the point at which BRG1 acts is unknown. The first IFN-gamma-induced event triggers nuclear translocation of STAT1 (signal transducer and activator of transcription 1), w...

In investigations of laminar or turbulent flows, wall shear is often important. Nevertheless, conventional particle image velocimetry (PIV) is difficult in near-wall regions. A near-wall measurement technique, named interfacial PIV (IPIV) [Nguyen, C., Nguyen, T., Wells, J., Nakayama, A., 2008. Proposals for PIV of near-wall flow over curved boundaries. In: Proceedings of 14th International Symp...

The present work involves the development of a particle imaging velocimetry system using an optical fiber bundle scope as shown in Figure 1. Applying a fiber scope to PIV system, the resolution of particle images is spatially poorer than those taken directly by a CCD camera, which leads to an inadequate result of cross-correlation between a pair of particle images from the fiber scope. With a c...

BACKGROUND In 2006, bronchiolitis due to adenovirus nosocomial infections resulted in the closure of a pediatric department in northern Portugal. OBJECTIVES To determine the etiology of bronchiolitis in northern Portugal. STUDY DESIGN It was a prospective multicenter study on the etiology of bronchiolitis during the respiratory syncytial virus (RSV) season (November-April). Children < or = ...

Particle image velocimetry (PIV) is a quantitative optical method used in experimental fluid dynamics that captures entire 2D/3D velocity field by measuring the displacements of numerous small particles that follow the motion of the Abstract A detailed statistical assessment of seedless velocity measurement using Schlieren Image Velocimetry (SIV) was explored using open source Robust Phase Corr...

Multiple plane stereo PIV results and data from a rake of ten hot-wire probes are used to investigate the largest scale structures in a zero-pressure-gradient turbulent boundary layer. Instantaneous vector fields from stereo PIV in spanwisestreamwise planes reveal long lowand high-speed regions, with a length that often exceeds the viewing window (> 2δ). Also evident is a remarkable degree of s...