Background—The safety and efficacy of the slow-release, polymer-based, paclitaxel-eluting stent after implantation in a broad cross section of de novo coronary lesions at 1 year are unknown. Methods and Results—In the TAXUS-IV trial, 1314 patients with single de novo coronary lesions 10 to 28 mm in length, with reference-vessel diameter 2.5 to 3.75 mm, coverable by a single study stent, were pr...

have a negligible impact on the analysis. Our findings of a more pronounced antirestenotic effect (P, 0.001) in Cypher vs. Taxus have actually raised concerns that most of the relative risk reduction apparent with Cypher was due to the severely inferior performance of Bx Velocity (a well-known thick strut BMS) when compared with the substantially superior performance of Cypher [when compared wi...

The presence of even mild renal insufficiency is usually associated with an increased rate of cardiovascular events after coronary stenting. The aim of this study was to evaluate the impact of mild to moderate renal insufficiency on the chronic vascular responses to the implantation of paclitaxel-eluting stents (PES; Taxus) and bare-metal stents (BMS). In the TAXUS IV, TAXUS V, and TAXUS VI tri...

Two new taxoids called 7,13-dideacetyl-9,10-debenzoyl-7beta,9alpha-p-hydroxylbenzylidenedioxy-taxchinin C (1) and 7,13-dideacetyl-2,9,10-debenzoyl-2-tigloyl-7beta,9alpha-p-hydroxylbenzylidenedioxy-taxchinin C (2) were isolated from the leaves and stems of Taxus chinensis. They represent the first examples of taxoids containing the 5/7/6-membered ring system with 7beta,9alpha-p-hydroxylbenzylide...

Erratum In the original publication [1] the species name Kutki (Neopicrorhiza scrophulariiflora) is wrongly mentioned as CITES listed species. The correct version of the sentence in the second paragraph of “Threats and conservation challenges” can be found here: Illegal trade of NTFPs from the landscape often includes some of the CITES Appendix listed species such as Sunakhari (Orchids) and Lau...

The Early Cretaceous Huolinhe Formation in eastern Inner Mongolia, northeastern China has yielded abundant and diverse plant fossils, to which we here add a new species of Taxus based on exceptionally well-preserved, lignified leaves from the Gucheng open-cast coal mine. huolingolensis sp. nov. linear with lamina that tapers an acute mucronate apex, narrows into decurrent, stalk-like base. midr...

Black vine weevils, Otiorhynchus sulcatus (F.) (Coleoptera: Curculionidae), are serious pests of container- and field-grown nursery crops. Management programs usually target the larval stage in container-grown plants and the adults in field-grown plants. We tested several new systemic insecticides for efficacy against black vine weevil in container-grown Sedum spp. and field-grown Taxus spp. In...

OBJECTIVES This study was conducted to determine whether direct stenting with TAXUS Liberté is noninferior to stenting after pre-dilation. BACKGROUND Direct stenting is performed in approximately 30% of patients, but data on clinical and angiographic outcomes with drug-eluting stents are limited. METHODS The TAXUS ATLAS DIRECT STENT is a single-arm, multicenter study that enrolled patients ...