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Cells of metazoan organisms respond to DNA damage by arresting their cell cycle to repair DNA, or they undergo apoptosis. Two protein kinases, ataxia-telangiectasia mutated (ATM) and ATM and Rad-3 related (ATR), are sensors for DNA damage. In humans, ATM is mutated in patients with ataxia-telangiectasia (A-T), resulting in hypersensitivity to ionizing radiation (IR) and increased cancer suscept...
Community and topic can help summarize the text-augmented social networks. Existing works mixed up community and topic by regarding them as the same. However, there is inherent difference between community and topic such that treating them as the same is not so flexible. We propose a mutual enhanced infinite community-topic model (MEI) to detect communities and topics simultaneously in text-aug...
Evidence is accumulating indicating that UVA (320-400 nm ultraviolet light) plays an important role in photo-carcinogenesis. UVA is thought to produce reactive oxygen species in irradiated cells through photo-activation of inherent photosensitizers, and was recently reported to cause DNA double-strand breaks (DSBs) in exposed cells. We have investigated the involvement of UVA in mutations and D...
با استفاده از mei نقش پدیدة جوّی- اقیانوسی انسو?در?تغییرپذیری بارش?های فصلی استان آذربایجان?شرقی مورد?مطالعه قرار?گرفته است.?نتایج حاصل از?بکارگیری روش تحلیل همبستگی «پیرسون» بیانگر ارتباط مثبت بین شاخص چند?متغیرة انسو و?بارش ایستگاه های آذربایجان?شرقی است که در?بین فصول چهار گانه میزان همبستگی فقط در?فصل پائیز? معنی دار?بوده و?در?سایر?فصول همبستگی معنی داری بین بارش و پدیده های ال نینو?و?لانینا...
Mapping the precise DNA sequence to which transcription factors bind contributes significantly to understanding the regulation of gene expression. In vitro footprinting techniques are typically employed to examine DNA-protein contacts (3). Methylation protection-based footprinting (MeP) is specifically used to identify the guanine contacts by a transcription factor because DMS will uniformly me...
A TRIAL WAS CONDUCTED TO i) evaluate the BW growth, energy intakes and energetic efficiency of pigs fed high and low density diets from 27 to 141 kg BW, ii) evaluate sire line and sex differences when fed both diets, and iii) to compare ME to NE as predictor of pig performance. The experiment had a replicated factorial arrangement of treatments including four sire lines, two sexes (2,192 barrow...
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