This study assesses the performance of model-assisted Design Experiment (mDoE) software toolbox for design two microalgae bioprocesses. The mDoE-toolbox was applied to maximize biomass growth Desmodesmus pseudocommunis in a photobioreactor by varying light intensity and pH Chlorella vulgaris shake flasks, duration. For both case studies, mathematical mechanistic model applied. In first only one...

To maintain the integrity of the US nuclear stockpile without detonating nuclear weapons, the DOE needs the results of computer-simulations that overwhelm the world’s most powerful supercomputers. Responding to this need, the DOE initiated the Accelerated Strategic Computing Initiative (ASCI). This program accelerates the development of new scalable supercomputers resulting in a TeraFLOP comput...

We introduce a previously unreported laser cavity configuration, using a diffractive optical element (DOE) in place of the output coupler. Such a configuration allows the DOE to work both in reflection, as a mode shaping element, and in transmission as a beam shaper. Employing dual wavelength DOE optimization techniques and phase delays greater than 2pi, allows the two functions to be designed ...

The U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a national user facility, serves the diverse scientific community by providing integrated high-throughput sequencing and computational analysis to enable system-based scientific approaches in support of DOE missions related to clean energy generation and environmental characterization. The JGI Genome Portal (http://genome.jgi.doe...