OBJECTIVE Doxorubicin (DOX) induces cardiac dysfunction. Paracetamol (APAP) has also been established as an effective cardioprotective agent during ischemia/reperfusion. Therefore, this study aims to evaluate the effect of APAP on DOX-induced cardiotoxicity in ischemia/reperfused isolated rat heart. METHODS A total of 36 rats were equally divided into four groups: control, DOX (30 min, 20 µM ...

PURPOSE Cardiovascular responses of traditional resistance (TS) training have been extensively explored. However, the fatigue mechanisms associated with an intra-set rest configuration (ISR) have not been investigated. This study compares two modalities of set configurations for resistance exercise that equates work to rest ratios and measures the central and peripheral fatigue in combination w...

BACKGROUND We carried out this study to compare the efficacy of oral gabapentin and clonidine premedication for controlling the pressor responses to laryngoscopy and tracheal intubation. METHODS In this double-blind clinical trial, ninety-six patients were randomly allocated to one of three groups according to the agents to be used before the induction of anaesthesia: Group P (n = 32) receive...

Spatial monitoring of tetracycline (TC)-resistant bacteria in sediments of the Mekong River watershed revealed that the main waterway showed a high occurrence rate of TC-resistant bacteria, whereas Tonle Sap Lake and the Sai Gon estuary did not. The Shannon index (H'), an indicator of ecological diversity, was calculated from denaturing gradient gel electrophoresis (DGGE) profiles, which indica...

Pressure natriuresis may be mediated through increases in inner medullary vasa recta blood flow (QvR). By means of acute renal decapsulation to prevent increases in renal interstitial hydrostatic pressure (RIHP), the effect of increases in QVR in the presence and absence of changes in RIHP in the natriuretic and diuretic responses to increases in renal perfusion pressure (RPP) was evaluated. Bl...

Determination of the factors influencing renal vascular resistance (RVR) at very low perfusion pressures (RPP) is of interest, since prolonged periods of reduced perfusion can lead to acute renal failure. We have studied the effects of inhibition of the renin-angiotensin system on renal blood flow (RBF), measured by electromagnetic flow probe, over a subautoregulatory pressure range of BOSS mm ...

INTRODUCTION Nonconvulsive seizures (NCS) are frequent in hospitalized patients and may further aggravate injury in the already damaged brain, potentially worsening outcomes in encephalopathic patients. Therefore, both early seizure recognition and treatment have been advocated to prevent further neurological damage. OBJECTIVE Evaluate the main EEG patterns seen in patients with impaired cons...

BACKGROUND Radical surgical resection as a treatment modality for oral cancer often leads to an extensive deficit in both the maxillary and mandibular levels, where the use of a palatal obturator prosthesis (POP) or removable partial denture (RPP). The aim of this study was to evaluate the treatment with POP and RPP in patients treated for oral cancer in the Unit of Prosthetic Rehabilitation of...

ویژگی‌های زیستی به‌ویژه رفتار تخمریزی زنبورهای پارازیتویید یکی از مهم‌ترین عوامل تعیین‌کننده کارایی آنها در مدیریت جمعیت آفت میزبان می‌باشد. این مطالعه الگوی وابسته به سن، نرخ پارازیتیسم، درصد تفریخ و نسبت جنسی زنبور Trichogramma brassicae روی Ephestia kuehniella شرایط آزمایشگاهی (1±25 درجه سلسیوس، رطوبت نسبی %5±70 دوره نوری 16: 8 ساعت (روشنایی: تاریکی)) بررسی شد. نتایج نشان داد T. سنین جوانی (...

PURPOSE Postprandial myocardial ischemia has been observed in frail older adults with postprandial hypotension and in patients with severe coronary artery disease, especially after high doses of carbohydrates. The impact of oral glucose on myocardial oxygen supply and demand in healthy older adults without postprandial hypotension or postprandial angina remains unexamined. We hypothesized that ...