A large body of evidence supports the protective role flavonol antioxidant compound quercetin in mammals. We tested hypothesis that can protect against hypothalamus-pituitary-gonadal (HPG) axis defect like a reduction gonadotropins and testicular hormones abnormal semen analysis induced by chronic unpredictable stress (CUS), possibly via downregulation oxidative (ROS) p53-Bax-caspase-3 pathways...

In the present study, to contribute to the understanding of the evolutionary history of sheep, the mitochondrial (mt) DNA polymorphisms occurring in modern Turkish native domestic (n = 628), modern wild (Ovis gmelinii anatolica) (n = 30) and ancient domestic sheep from Oylum Höyük in Kilis (n = 33) were examined comparatively with the accumulated data in the literature. The lengths (75 bp/76 bp...

To optimally time reproduction, animals must coordinate changes in the hypothalamo-pituitary-gonadal (HPG) axis. The extent of intra-species variation in seasonal timing of reproductive function is considerable, both within and among populations. Dark-eyed junco (Junco hyemalis) populations are known to differ in their reproductive timing response to cues experienced in the same habitat in late...

Em homens obesos, é esperada a presença de níveis baixos testosterona (TT) devido à conversão da TT em estradiol pela enzima aromatase. De forma contraria, no hipogonadismo compensado (HC) espera-se que o eixo hipotálamo-hipófise-gonadal (HPG) aumente hormônio (LH), já os tendem diminuir.

Germinal damage is an almost universal accompaniment of cancer treatment as the result of bystander damage to the testis from cytotoxic drugs and/or irradiation. Cancer treatment for the most common cancers of the reproductive age group in men has improved such that most are now treated with curative intent, and many others are treated with likelihood of prolonged survival, so that the preserva...

Hypogonadism, whether caused by the failure of gonadal development or function, frequently results in bone loss. In a research article in the April 21, 2006 issue of Cell, Sun et al. investigated the role of follicle-stimulating hormone (FSH) in the bone loss that is characteristic of hypogonadal mice. They report that female mice lacking either FSHβ or its receptor (FSHR) are resistant to bone...

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