Alkaline elution was done on a variety of cells following cyclophosphamide (CY) treatment in vivo. Cells used were L1210 leukemia, normal mouse bone marrow, and peripheral blood cells obtained from a patient with chronic lymphatic leukemia (CLL). Endpoints used were determination of single strand breaks, DNA-DNA interstrand and DNA-protein cross-links. After treatment of mice with CY (4 mg/mous...

Mice bearing a large s.c. MOPC-315 tumor can be cured by a dose of cyclophosphamide (CY) ranging from 15 to 200 mg/kg. However, the low (15 mg/kg) and the high (200 mg/kg) doses mediate tumor eradication via different mechanisms. Tumor eradication by the low dose of drug requires the cooperation of the toxic effect of the drug and T-cell-dependent antitumor immunity. On the other hand, tumor er...

An explicit formula for the Mahler measure of the 3-variable Laurent polynomial a+ bx−1+ cy + (a+ bx+ cy)z is given, in terms of dilogarithms and trilogarithms. 2000 Mathematics Subject Classification. 11R06.

In this lecture we learn to solve nonhomogeneous equations of the form ay′′ + by′ + cy = g(t) using the “method of undetermined coefficients”. In previous lectures we learned to how to solve any equation of the form ay′′ + by′ + cy = 0. We will apply these techniques to help us solve the nonhomogeneous equation ay′′ + by′ + cy = g(t) by understanding the connection between solutions to homogene...

Anthocyanins are natural pigments that could be involved in various health effects. Red oranges are an important dietary source of anthocyanins, including cyanidin 3-glucoside (Cy 3-glc) and an acylated derivative, cyanidin 3-(6''-malonyl)-glucoside (Cy 3-malglc). The aim of this study was to evaluate the absorption and metabolism of red orange anthocyanins in rats fed an anthocyanin-enriched d...

Combination of cyclophosphamide (CY) and passive immunization with lymphoid cells sensitized to allogeneic tumor was studied in the treatment of a methylcholanthrene-induced transplantable fibrosarcoma in WKA rats. For determination of the most effective timing of combination treatment, rats given an injection of CY on Day 3 received passive transfer of the sensitized lymphoid cells on Day 0, 1...

[Purpose] This study aimed to evaluate the mediating effect of gross motor function, measured using the Gross Motor Function Measure (GMFM) and of general function, measured using the International Classification of Functioning, Disability and Health-Child and Youth Check List (ICF-CY), on the ICF domains of activity and participation in children with cerebral palsy (CP). [Subjects] Ninety-five...

به منظور ارتقای سطح کیفی فضاهای مسکونی، در این پژوهش هدف کشف عوامل مؤثر بر کیفیت محیط ارتباط بین آن‌ها و بیان راهبردهایی همین است. مسکونی مفهومی پویا، پیچیده، چندبعدی است که از ابعاد مختلف کالبدی، اجتماعی، اقتصادی، زیست‌‌محیطی شکل گرفته معیارهای مناسب ارزیابی سنجش رضایتمندی ساکنان آن ماهیت اما دلیل استخراج قابل‌اندازه‌‌گیری تلفیقی روش‌‌های کمّی قالب شیوۀ همبستگی استفاده شده با تبیین الگوی معادله...