The aim of the present study was to determine the mechanisms underlying the relaxant effect of adrenomedullin (AM) in rat cavernosal smooth muscle (CSM) and the expression of AM system components in this tissue. Functional assays using standard muscle bath procedures were performed in CSM isolated from male Wistar rats. Protein and mRNA levels of pre-pro-AM, calcitonin receptor-like receptor (C...

Early-time light curves/spectra of some hydrogen-rich supernovae (SNe) give firm evidence on the existence confined, dense circumstellar matter (CSM) surrounding dying massive stars. We numerically and analytically study radiative acceleration CSM in such systems, where radiation is mainly powered by interaction between SN ejecta CSM. find that unshocked ahead shock larger for compact CSM, with...

Plasma and tissue concentrations of total, (+)- and (-)-gossypol were determined in broilers fed cottonseed meals (CSM) from eight oil mills (five expander solvent, two expeller, and one direct solvent). Free gossypol in the meals ranged from 0.033 to 0.180%, and total gossypol ranged from 0.974 to 1.459%. The (+)-enantiomer of gossypol varied from 53.8 to 61.3% of total gossypol. Eight CSM die...

Background Cervical sagittal alignment plays an important role in the pathogenesis of cervical spondylotic myelopathy (CSM), but there are limited studies on the cervical sagittal parameters in CSM patients and their correlations with myelopathy. The aim of this study is to investigate the correlations among the preoperative cervical sagittal alignment parameters and their correlations with the...

OBJECTIVE To determine the risk of cancer-specific mortality (CSM) versus the competing risk of mortality by other causes (MOC) in patients with localised prostate cancer (LPC) treated with radical prostatectomy (RP). MATERIAL AND METHOD An observational cohort study of 982 patients with LPC treated with RP selected from our department's PC registry database. A competing risk analysis was per...

MAHDI HASAN, SANDEEP TRIPATHI, ABBAS ALI MAHDI, KALYAN MITRA and MAHENDRA PAL SINGH NEGI INSA Honorary Scientist, Department of Anatomy, CSM Medical University, Lucknow-226003, India Department of Biochemistry, CSM Medical University, Lucknow-226003, India Electron Microscopy Division, Central Drug Research Institute, Lucknow-226001, India Biometry and Statistics Division, Central Drug Research...

PURPOSE The purpose of this study was to evaluate the risk of cardiac death in pediatric Hodgkin's lymphoma (HL) survivors and identify high-risk groups that may need additional surveillance. METHODS The Surveillance, Epidemiology and End Results program database was queried to analyze the rates of radiation therapy (RT) use and cardiac-specific mortality (CSM) in HL patients, aged 0-21 years...

Introduction: Details of surgical and general complications for patients with cervical spondylotic myelopathy (CSM) are still uncertain. The purpose of this study was to describe surgeries and their complications among Japanese patients with CSM. Methods: The Japanese Society for Spine Surgery and Related Research performed a nationwide survey on spine surgery and complications in 2011. Data of...