Deconstruction of molecular pathways and advances in enabling technology platforms have opened new horizons for disease management, exploring therapeutic solutions to each individual patient beyond the one-size fits all practice. Application of personalized medicine paradigms aims to achieve the right diagnosis and right treatment for the right patient at the right time at the right cost. With ...

BACKGROUND Traditional Chinese Medicine (TCM), a complementary and alternative medical system in Western countries, has been used to treat various diseases over thousands of years in East Asian countries. In recent years, many herbal medicines were found to exhibit a variety of effects through regulating a wide range of gene expressions or protein activities. As available TCM data continue to a...

BACKGROUND Despite strict avoidance, severely food-allergic children experience frequent and potentially severe food-induced anaphylaxis (FSFA). There are no accepted preventive interventions for FSFA. A Traditional Chinese Medicine (TCM) formula prevents anaphylaxis in murine food allergy models, and has immunomodulatory effects in humans. We analyzed the effects of TCM treatment on three pedi...

Background: Traditional Chinese medicine (TCM) has shown excellent therapeutic effects in the treatment of heart diseases. This meta-analysis was to evaluate TCM on patients with atrial fibrillation (AF).

The metal-organic framework copper(i) tricyanomethanide, Cu(tcm), undergoes a ferroelastic transition on cooling below Tf = 240 K. Thermal expansion measurements reveal an order-of-magnitude variation in framework flexibility across Tf. The low-temperature phase α-Cu(tcm) exhibits colossal positive and negative thermal expansion that is the strongest ever reported for a framework material. On e...

Takotsubo cardiomyopathy (TCM) is a medical condition characterized by a transient left ventricular apical dysfunction with unknown etiology. The clinical presentation mimics acute myocardial syndrome in the absence of obstructive coronary artery disease. The association between acute pancreatitis and TCM, however, is rarely reported in the literature. To date, no cases of TCM resulting from th...

Traditional Chinese Medicine (TCM) is a range of medical practices used in China for more than four millenniums, a treasure of Chinese people (Lukman, He, & Hui, 2007). The important role of TCM and its profound influence on the health care system in China is well recognized. The West also has drawn the attention towards various aspects of TCM in the past few years (Chan, 1995). TCM consists of...

Objective. To observe the effects of empirical prescriptions of traditional Chinese medicine (TCM) on inflammatory mediators in pediatric asthma and to explore the underlying molecular mechanism in the treatment of asthma. Methods. A total of 182 children with asthma were randomly placed into either the TCM group (n = 97) or the salbutamol and montelukast (SM) group (n = 85). Patients in the TC...