OBJECTIVE To compare symptomatic and objective outcomes between HM and POEM. BACKGROUND The surgical gold standard for achalasia is laparoscopic Heller myotomy (HM) and partial fundoplication. Per-oral endoscopic myotomy (POEM) is a less invasive flexible endoscopic alternative. We compare their safety and efficacy. METHODS Data on consecutive HMs and POEMs for achalasia from 2007 to 2012 w...

This paper develops a framework for regional scale flood modeling that integrates NEXRAD Level III rainfall, GIS, and a hydrological model (HEC-HMS/RAS). The San Antonio River Basin (about 4000 square miles, 10,000 km2) in Central Texas, USA, is the domain of the study because it is a region subject to frequent occurrences of severe flash flooding. A major flood in the summer of 2002 is chosen ...

Board & Chung [3] propose a class of structures (OBU structures) designed to model agents’ awareness of their own unawareness. In particular, OBU structures are capable of modeling an agent who is “not sure whether or not she is aware of everything”, without the implication that she does not know what she is aware of. In Board & Chung [3] (henceforth BC), OBU structures were used to provide sem...

1141 December 2014 W E are delighted that AnEsthEsiology is publishing this special Edition, highlighting research at the harvard-affiliated departments. harvard Medical school (hMs) is unusual, perhaps unique, in that it has approximately 10,000 faculty appointees, including many physicians with additional appointments at multiple affiliated and financially independent academic hospitals that ...

Hemimasticatory spasm is a rare neurologic disorder characterized by unilateral, paroxysmal involuntary contraction of the masticatory muscles. It can be confused with other unilateral facial spasms. In this report, we present two patients with hemimasticatory spasm who were initially misdiagnosed with other disorders. The first patient was a 54-year-old man with a 9-year history of right facia...

OBJECTIVES To assess the relationship between social integration and physical and mental health among humanitarian migrants (HMs) in Australia. DESIGN, SETTING AND PARTICIPANTS We used the recently released first wave of data from the 2013 'Building a New Life in Australia' survey, which is an ongoing nationwide longitudinal study. A total of 2399 HMs participated in the survey. MAIN OUTCOM...

BACKGROUND Corneal biometric parameters can possibly be influenced by high myopia (HM). The influence of HM on corneal thickness (CT), epithelial thickness (ET) has not yet been clearly established. The aim of this study is to observe ET, CT and axial length (AL) differences between in normal and subjects with HMs and to investigate factors influencing the corneal biometric parameters and AL, s...

The Harvard Medical School-Cambridge Integrated Clerkship (HMS-CIC) is a redesign of the principal clinical year to foster students' learning from close and continuous contact with cohorts of patients in the disciplines of internal medicine, neurology, obstetrics-gynecology, pediatrics, and psychiatry. With year-long mentoring, students follow their patients through major venues of care. Surger...

STUDY QUESTION How does tetraploidy develop in hydatidiform moles (HMs), and what is the frequency of the different origins? SUMMARY ANSWER Most molar pregnancies with tetraploid cells appear to be produced by somatic endoreduplications, while a minority originate from a tetraploid zygote. The frequency of zygotic tetraploidy was estimated to be 0.7%. WHAT IS KNOWN ALREADY The parental orig...

Bornelöv, S. 2014. Rule-based Models of Transcriptional Regulation and Complex Diseases. Applications and Development. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1167. 69 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9005-8. As we gain increased understanding of genetic disorders and gene regulation more focus has turned to...