The cytoskeletal changes that alter cellular morphogenesis and motility depend upon a complex interplay among molecules that regulate actin, myosin, and other cytoskeletal components. The Rho family of GTP binding proteins are important upstream mediators of cytoskeletal organization. Gem and Rad are members of another family of small GTP binding proteins (the Rad, Gem, and Kir family) for whic...

OBJECTIVE To assess the impact of rapid aneuploidy detection (RAD) combined with fetal karyotyping versus karyotyping only on maternal anxiety and health-related quality of life. METHODS Women choosing to undergo amniocentesis were selected into group 1, i.e. receiving a karyotype result only (n = 132) or to group 2, i.e. receiving both the result of RAD and karyotyping (n = 181). RESULTS T...

TOPIC Attachment theory and reactive attachment disorder (RAD). PURPOSE To highlight current perspectives on attachment theory, RAD, and treatment implications using a case study of an 8-year-old patient with RAD. SOURCES Selected multidisciplinary literature related to attachment theory and RAD. CONCLUSIONS The literature provides a body of work that substantiates the importance of early...

Employment or Leadership: None declared. Consultant or Advisory Role: None declared. Stock Ownership: None declared. Honoraria: None declared. Research Funding: Bio-Rad Laboratories, ddPCR Reagents, Life Technologies, Acrometrix inhibition panel; K.R. Jerome, Bio-Rad Laboratories. Expert Testimony: None declared. Patents: None declared. Other Remuneration: T.C. Dingle, Bio-Rad Laboratories prov...

The inhibitory effects of 250 KVP x-radiation on the electroretinographic response (ERG) of the rabbit were investigated. Rabbits were exposed (head only) to either a single dose ranging from 3,000 rad to 8,000 rad or to a fractionated dose, two doses of 3,000 rod each with an interval of 5 days. ERG responses of the dark adapted eyes of the rabbit were determined prior to exposure and at vario...

BACKGROUND Little is known about the specific reasons for antipsychotic discontinuation or continuation from patients' or clinicians' perspectives. This study aimed to assess the construct validity of 2 new measures of the Reasons for Antipsychotic Discontinuation/Continuation (RAD): RAD-I (a structured interview assessing the patient's perspective) and RAD-Q (a questionnaire assessing the clin...

هدف: پژوهش حاضر با هدف بررسی مقایسه اثربخشی گروه درمانی شناختی – رفتاری و ذهن ­آگاهی مبتنی بر شناخت کاهش رفتارهای پرخطر در معتادان ترک افیونی صورت گرفت. روش: روش این شبه آزمایشی طرح پیش آزمون پس همراه کنترل است. جامعه­ی آماری شامل کلیه افراد وابسته به مواد مراجعه کننده مرکز اعتیاد شبکه بهداشت درمان شهرستان سرپل ذهاب نیمه اول سال 1396 بود، نمونه­ گیری دسترس تعداد 36 نفر تشخیص وابستگی اساس معیاره...