this study documents the flavonoid constituents of seven salvia species in iran namely s.atropatana bunge, s. limbata c. a. mey, s. sclarea l., s. ceratophylla l., s. multicaulis vahl.,s. hydrangea dc. ex benth., and s. eremophila boiss. the studied species were collected fromtheir natural habitats in iran and were analyzed for their flavonoid constituents using twodimensionalthin layer chromat...

Salvia miltiorrhiza (S. miltiorrhiza) Bunge is broadly used as herbal medicine for the clinical treatments of cardiovascular and cerebrovascular diseases. Despite its commercial and medicinal values, few systematic studies on the metabolome of S. miltiorrhiza roots have been carried out so far. We systematically described the metabolic profiles of S. miltiorrhiza using high pressure liquid chro...

Astragalus mongholicus Bunge has long been used to treat cardiovascular disease in Chinese traditional medicine. However, its mechanisms are not fully understood. In this study, we explored potential mechanisms and protective effects of total flavonoids of Astragalus (TFA) on cardiovascular disease using in vitro experiments and diet-induced atherosclerotic rabbits. We identified six components...

Cryptotanshinone (CPT) is the main pharmacologically active component of Salvia miltiorrhiza Bunge, and has been demonstrated to have inhibitory effects on a variety cancer cell types. However, target(s) CPT in colorectal (CRC) cells are still be identified. The aim this study was investigate molecular mechanism CPT-induced apoptosis CRC cells. Transcriptome sequencing revealed that 1234 genes ...

BACKGROUND Extracts from Salvia miltiorrhiza Bunge have been used in traditional Asian medicine to treat coronary heart disease, chronic renal failure, atherosclerosis, myocardial infraction, angina pectoris, myocardial ischemia, dysmenorrheal, neurasthenic insomnia, liver fibrosis and cirrhosis. The aim of the study was to investigate the anti-RANK signal effect of the combination of S.miltior...