Abstract In a follow-up to the investigations of soft ticks identified from seabird nest soil and litter collected coastal islands Republic Korea (ROK), Ornithodoros sawaii capensis were assessed for presence identification rickettsiae. Ticks samples 50–100 g nests individually by morphological techniques, species confirmed sequencing mt-rrs gene. Subsequently, tick DNA preparations screened ri...

Protection: Support From Studies in Bartter and Gitelman Syndrome To the Editor: In a recent article, Wolfrum et al1 have shown that in human cells in culture, inhibition of Rho kinase (RKO) activates Akt pathway, which they contend leads to cardiovascular protection via activation of eNOS. ROK (a downstream effector of RhoA G protein) involvement has been advanced in the pathogenesis of hypert...

Rocznik Biblioteki Naukowej PAU i PAN » Rok LXVII (2022) Sprawozdanie z ogólnopolskiej konferencji naukowej Spuścizny w zbiorach archiwalnych, bibliotecznych muzealnych bazÄ ÅºródłowÄ badaniach biograficznych, Kalisz, 22–23 IX 2022 A

OBJECTIVES In this study, we demonstrated that TBEV-infected ticks have been distributed in the ROK, combined with our previous results. These results suggest that TBEV may exist in the ROK, and H. longicornis, H. flava, and I. nipponensis may be potential vectors of TBEV. In addition, these results emphasize the need for further epidemiological research of TBEV. METHODS We examined for the p...

BACKGROUND Emerging respiratory infections represent a significant public health threat. Because of their novelty, there are limited measures available to control their early spread. Learning from past outbreaks is important for future preparation. The Middle Eastern Respiratory Syndrome CoronaVirus (MERS-CoV ) 2015 outbreak in the Republic of Korea (ROK) provides one such opportunity. OBJECT...

Myosin-based contractility plays important roles in the regulation of epithelial functions, particularly paracellular permeability. However, the triggering factors and the signaling pathways that control epithelial myosin light chain (MLC) phosphorylation have not been elucidated. Herein we show that plasma membrane depolarization provoked by distinct means, including high extracellular K(+), t...

RhoA/Rho-kinase (RhoA/ROK) pathway promotes vasoconstriction by calcium sensitivity mechanism. LPS causes nitric oxide (NO) overproduction to induce vascular hyporeactivity. Thus, we tried to examine the role of RhoA/ROK and NO in the regulation of vascular reactivity in different time-point of endotoxaemia. Male Wistar rats were intravenously infused for 10 min with saline or E. coli endotoxin...