The "large" (LG/J) and "small" (SM/J) inbred mouse strains differ for a wide variety of traits related to body size and obesity. Ninety-three LG/J and SM/J mice were divided into two treatment categories and fed a moderately high-fat diet (21% kcal fat) or a low-fat diet (12% kcal fat) from weaning to necropsy. Strain differences in obesity-related traits and differential response to dietary fa...

BACKGROUND/AIMS Cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF) are up-regulated in hepatocellular carcinoma (HCC). To investigate the levels of COX-2 and VEGF expression in chronic hepatitis (CH), cirrhosis, and HCC. METHODS The immunohistochemical expressions of COX-2 and VEGF were evaluated in tissues from patients with CH (n=95), cirrhosis (n=38), low-grade HCC (LG-...

Yeast flocculation is a phenomenon which is believed to result from an interaction between a lectin-like protein and a mannose chain located on the yeast cell surface. The FLO1 gene, which encodes a cell wall protein, is considered to play an important role in yeast flocculation, which is inhibited by mannose but not by glucose (mannose-specific flocculation). A new homologue of FLO1, named Lg-...

This study examined the narratives of 82 adoptive parents (41 couples: 15 lesbian, 15 gay male, 11 heterosexual) of young children (M age = 5.81 years) with a focus on understanding parents’ socialization practices and strategies surrounding race (among parents of children of color), and family structure (among lesbian or gay [LG] parents). Most parents described an engaged approach to socializ...

To study the local Hubble flow, we have run constrained dark matter (DM) simulations of the Local Group (LG) in the concordance ΛCDM and OCDM cosmologies, with identical cosmological parameters apart from the Λ term. The simulations were performed within a computational box of 64 hMpc centred on the LG. The initial conditions were constrained by the observed peculiar velocities of galaxies and ...

Study Design: Thirty beagle dogs underwent 2 hours of hepatic vascular exclusion using venovenous bypass. Misoprostol was administered intravenously for 30 minutes before ischemia and for 3 hours after reperfusion. o P -41483 was administered intraportally for 30 minutes before ischemia (2#Lg/kg/min) and for 3 hours after reperfusion (0.5 #Lg/kg/min). Animals were divided into five groups: untr...

INTRODUCTION The lacrimal gland (LG) of the CD25-/- model of Sjögren's syndrome (SS) has high interleukin (IL)-17, IL-13 and interferon-gamma (IFN-γ) cytokines. The specific contribution of these cytokines to the onset and severity of dacryoadenitis in the CD25-/- mice has not been evaluated. METHODS CD25-/-IL-17A-/-, CD25-/-IL-17-/-IFN-γ-/- and CD25-/-IFN-γ-/- were used at 4, 8, 12, 16 weeks...

We read with interest the article by Lota et al. The authors report a case of lymphomatoid granulomatosis (LG) with an atypical CT finding of crescent sign for LG. Typically, LG patients with lung involvement can present with pulmonary infiltration and may later develop a reversed halo sign, a focal round area of ground-glass attenuation and surrounding airspace consolidation of crescent shape....