OBJECTIVE The aim of this study was to analyze the histopathological and immunohistochemical characteristics of 22 cases of primary oral melanomas (OM). STUDY DESIGN Twenty two cases of primary oral melanoma were analyzed by description of their histopathological features and immunohistochemical study using the antibodies S-100, HMB-45, Melan-A and Ki-67. RESULTS The mean age was 58 years a...

The reactions of [CpMoH(κ(3)-P4)] (2; P4 = meso-o-C6H4(PPhCH2CH2PPh2)2) with protic acids gave [CpMo(κ(4)-P4)](+) (4(+)) via the intermediary formation of [CpMoH2(κ(3)-P4)](+). Treatment of 2 with iodine provided the cationic complex [CpMoHI(κ(3)-P4)][I] (5[I]). Early-late heterobimetallic complexes of the type [CpMoH(μ-P4-1κ(3):2κ)MLnCl] (MLn = Ru(Hmb)Cl (6), Ir(η(5)-C5Me5)Cl (7), Rh(cod), Ir(...

The current project examined the impact of differential motivation on baseline versus post-mild traumatic brain injury (MTBI) neuropsychological measures in athletes. Collegiate athletes were administered a neuropsychological battery prior to and post-MTBI. High Motivation at Baseline (HMB) and Suspect Motivation at Baseline (SMB) groups were established for each measure based on whether baseli...

OBJECTIVES SOX-10 has been shown to be a sensitive marker of cutaneous melanoma. This study aimed to evaluate Sox-10 expression in uveal melanoma. METHODS A total of 40 tissue blocks of enucleated eyes with uveal melanoma were cut and stained using an anti-SOX-10 mouse monoclonal antibody and HMB-45 antibody. RESULTS SOX-10 showed exclusive nuclear positivity in 100% of the uveal melanoma c...

We revisit sheaves on locales by placing them in the context of the theory of Hilbert quantale modules. The local homeomorphisms p : X → B are identified with the locales X that are Hilbert B-modules equipped with a natural notion of basis. These modules form a full subcategory B-HMB of the category of Hilbert B-modules where all the homomorphisms are adjointable: for each homomorphism h there ...

Eley HL, Russell ST, Tisdale MJ. Attenuation of depression of muscle protein synthesis induced by lipopolysaccharide, tumor necrosis factor, and angiotensin II by -hydroxy-methylbutyrate. Am J Physiol Endocrinol Metab 295: E1409–E1416, 2008. First published October 14, 2008; doi:10.1152/ajpendo.90530.2008.— -Hydroxymethylbutyrate (HMB; 50 M) has been shown to attenuate the depression in protein...

Abstract: In order to overcome the shortcoming of magnetic bearings whereby general mathematical models of the radial suspension forces cannot be accurately established, a mathematical model considering the edge effect is set up. The configuration, operation principle and flux distribution features of a three-pole radial hybrid magnetic bearing (HMB) are analyzed in this paper. The magnetic fie...

During ethylene biosynthesis, the H(3)CS- group of S-adenosylmethionine is released as 5'-methylthioadenosine, which is recycled to methionine via 5-methylthioribose (MTR). In mungbean hypocotyls and cell-free extracts of avocado, [(14)C]MTR was converted into labeled methionine via 2-keto-4-methylthiobutyric acid (KMB) and 2-hydroxy-4-methylthiobutyric acid (HMB), as intermediates. Incubation ...

BACKGROUND Histologic diagnosis of mucosal melanoma of the head and neck is difficult, requiring immunohistochemical stains which are less reliable than in cutaneous lesions. PNL-2 is a novel marker that has not been examined in mucosal melanoma. METHODS Nine formalin-fixed tissue sections of mucosal melanoma were stained with PNL-2, human melanoma black (HMB)-45, Melan-A, S-100, and micropht...