OBJECTIVE GTP cyclohydrolase I (GCH1) is the rate-limiting enzyme for tetrahydrobiopterin biosynthesis and has been shown to be a promising therapeutic target in ischemic heart disease, hypertension, atherosclerosis and diabetes. The endogenous GCH1-interacting partners have not been identified. Here, we determined endogenous GCH1-interacting proteins in rat. METHODS AND RESULTS A pulldown an...

This paper describes the results of experimental testing of glass fiber reinforced plastic (GFRP) composite beam strengthened reinforced concrete (RC) slabs with two symmetrical openings. Specimens, one-half scale, have been designed and fabricated to reflect the most common RC bathroom slab used in school buildings. The specimen had dimensions of 2000 mm (width) × 150 mm (thickness) × 3000 mm ...

This work addresses the assessment of the electromagnetic disturbance induced by a composite barrier—fencing airport structures—to radio-communication electromagnetic waves. The barrier is composed of glass fiber reinforced polymer GFRP tubular elements installed into a concrete base. Based on the electromagnetic properties of constituent materials, numerical analyses describing the electromagn...

An assembled plane truss structure used for vehicle loading is designed and manufactured. In the truss, the glass fiber reinforced polymer (GFRP) tube and the steel joint are connected by a new technology featuring a pretightened tooth connection. The detailed description for the rod and node design is introduced in this paper, and a typical truss panel is fabricated. Under natural conditions, ...

A non-destructive testing method on Glass Fibre Reinforced Polymer (GFRP) after high velocity impact event using single stage gas gun (SSGG) is presented. Specimens of Ctype and E-type fibreglass reinforcement, which were fabricated with 6mm, 8mm, 10mm and 12mm thicknesses and size 100 mm x 100 mm, were subjected to a high velocity impact with three types of bullets: conical, hemispherical and ...

Experimental design and response surface methodology (RSM) were used to optimize the modification of conditions for glass surface grafting with acrylamide (AM) monomer for preparation of a glass fiber reinforced poly(vinylidene fluoride) (PVDF) composite membrane (GFRP-CM). The factors considered for experimental design were the UV (ultraviolet)-irradiation time, the concentrations of the initi...

The prerequisite for more competent and cost effective transport has led to the evolution of innovative testing and evaluation procedures. Non-destructive testing and evaluation (NDT & E) techniques for assessing the integrity of composite structures are essential to both reduce manufacturing costs and out of service time of transport means due to maintenance. Smart methods for assessing the in...

Abstract Developments in polymer technology have introduced new choices such as using fibers and fiber-reinforced polymers (FRP) to improve the impact behavior of concrete structures. In this research, 52 samples (half which wrapped with glass polymers-GFRP) different compressive strengths (20, 30, 40 MPa) polypropylene were constructed. These subjected weight dropping (46.7 kg 66.8 kg). The nu...

Glass fiber reinforced polymer (GFRP) is a typical difficult-to-process material. Its drilling quality directly affected by the processing technology and tool life; burrs, tearing, delamination other defects will reduce service life of GFRP structural parts. Through damage wear experiments GFRP, thrust force, vibration amplitude, number processed holes, feed rate cutting speed were found to be ...