PB1-F2, a protein encoded by a second open reading frame of the influenza virus RNA segment 2, has emerged as a modulator of lung inflammatory responses but the molecular mechanisms underlying this are only poorly understood. Here we show that PB1-F2 inhibits the activation of NF-κB dependent signalling pathways in luciferase reporter assays. PB1-F2 proteins from four different viruses interact...

The glass transition in binary mixtures of star polymers is studied by mode coupling theory and extensive molecular dynamics computer simulations. In particular, we have explored vitrification in the parameter space of size asymmetry δ and concentration F2 of the small star polymers at fixed concentration of the large ones. Depending on the choice of parameters, three different glassy states ar...

We explore tensor mesons in AdS/QCD focusing on f2(1270), the lightest spin-two resonance in QCD. We find that the f2 mass and the partial width Γ(f2 → γγ) are in very good agreement with data. In fact, the dimensionless ratio of these two quantities comes out within the current experimental bound. The result for this ratio depends only on Nc and Nf , and the quark and glueball content of the o...

In classical fixed point and coincidence theory the notion of Nielsen numbers has proved to be extremely fruitful. We extend it to pairs (f1, f2) of maps between manifolds of arbitrary dimensions, using nonstabilized normal bordism theory as our main tool. This leads to estimates of the minimum numbers MCC(f1, f2) (and MC(f1, f2), resp.) of pathcomponents (and of points, resp.) in the coinciden...

This study examined the contribution of F1 and F2 alone on the perception of plosive consonants in a CV context. Applying a 3-Bark spectral integration the F2 frequency was corrected for effects of proximity either to F1 or to F3, i.e., was replaced by F2’. Subjects used a two-dimensional Method of Adjustment to select the F1 and F2 consonant onset frequencies that led to a subjectively optimal...