1 EE Dept., The Pennsylvania State University. University Park, PA 16802, USA, [email protected] 2 EE Dept., The Pennsylvania State University. University Park, PA 16802, USA, [email protected] 3 EE Dept., The Pennsylvania State University. University Park, PA 16802, USA, [email protected] 4 EE Dept., The Pennsylvania State University. University Park, PA 16802, USA, [email protected]....

Faldaprevir is a potent hepatitis C virus (HCV) NS3/4A protease inhibitor. Faldaprevir is known to inhibit P-glycoprotein, CYP3A4, and UDP-glucuronosyltransferase 1A1. This study evaluated the effect of steady-state 240 mg faldaprevir on the pharmacokinetics (PK) of an oral contraceptive containing ethinylestradiol (EE) and levonorgestrel (LNG) in healthy premenopausal women. In period 1, subje...

BACKGROUND Environmental enrichment (EE) in laboratory animals improves neurological function and motor/cognitive performance, and is proposed as a strategy for treating neurodegenerative diseases. EE has been investigated in the R6/2 mouse model of Huntington's disease (HD), where increased social interaction, sensory stimulation, exploration, and physical activity improved survival. We have a...

Probability theory has been traditionally used to characterize both types of uncertainty. E.g. aleatory uncertainty can be best dealt with using the frequentist approach associated with traditional probability theory. However, probability theory is not capable of completely capturing epistemic uncertainty. The traditional method was called Bayesian Probability. In this method, it is necessary t...

91 EE&S 820 Environmental Systems Analysis 3(3,0) Analysis of a systems view of environmental problems, with particular emphasis on conflicting objectives such as economic and environmental concerns. Example problems span traditional environmental engineering processes, natural resources, proactive environmental management, and sustainability. Preq: MTHSC 311 or consent of instructor. EE&S 832 ...

A sizeable body of research has demonstrated that expressed emotion (EE) predicts clinical relapse in a number of distinct psychiatric disorders. These findings have provided the impetus for the development of interventions that attempt to reduce patients' relapse rates by modifying aspects of the family environment believed to be associated with high levels of EE. Despite the efficacy of these...

The aim of this study was to compare the energy expenditure (EE) estimations of activity-specific prediction equations (ASPE) and of an artificial neural network (ANNEE) based on accelerometry with measured EE. Forty-three children (age: 9.8 ± 2.4 yr) performed eight different activities. They were equipped with one tri-axial accelerometer that collected data in 1-s epochs and a portable gas an...

BACKGROUND Increasing daily energy expenditure (EE) plays an important role in the prevention or treatment of several lifestyle-related diseases; however, its measurement remains problematic. OBJECTIVE The objective was to evaluate a portable armband device for measuring daily and physical activity EE compared with doubly labeled water (DLW) in free-living individuals. DESIGN Daily EE and p...

Background/purpose: Gastroesophageal reflux disease (GERD) can be classified as erosive esophagitis (EE) or non-erosive reflux disorder (NERD) by endoscopic findings. The aim of this study was to investigate the effect of gender on symptom presentation and quality of life of patients with EE and NERD. Methods: Data from patients with GERD were collected between January and December 2009. The en...