In the title compound, C(12)H(11)N(5)O(2), the mol-ecule adopts an E configuration, with the benzene and pyrazine rings located on opposite sides of the N=C double bond. The face-to-face separations of 3.413 (14) and 3.430 (8) Å, respectively between parallel benzene rings and between pyrazine rings indicate the existence of π-π stacking between adjacent mol-ecules. The crystal structure also c...

The title compound, C(11)H(16)O(4), crystallizes with three molecules in the asymmetric unit. The cyclo-hexane ring adopts a chair conformation. Inter-molecular O-H⋯O hydrogen bonds are observed and these help to establish the crystal packing.

The mol-ecule of the title compound, C(14)H(10)N(2)O(2), adopts the phenol-imine tautomeric form. The dihedral angle between the planes of the two benzene rings is 13.84 (13)°. A strong intra-molecular O-H⋯N hydrogen-bonding inter-action stabilizes the mol-ecular conformation. In the crystal structure, centrosymmetrically related mol-ecules are linked into dimers by inter-molecular C-H⋯O and O-...

The title mol-ecule, C(12)H(9)NO(2), adopts a trans configuration about the olefinic double bond. The dihedral angle between the naphthalene ring system (r.m.s. deviation = 0.012 Å) and the nitro-ethenyl group (r.m.s. deviation = 0.032 Å) is 12.66 (5)°. The mol-ecules are linked into a two-dimensional network parallel to the bc plane by C-H⋯O hydrogen bonds. The substituted benzene rings in adj...

In the title Schiff base, C(15)H(15)NO, the benzene rings form a dihedral angle of 74.91 (1)°. There is a strong intra-molecular O-H⋯N hydrogen bond.

In the title compound, C(10)H(13)N(3)O(3), the 3,4-dimeth-oxy-benzyl-idene and hydrazinecarboxamide groups are oriented at a dihedral angle of 53.82 (6)° and an intra-molecular N-H⋯N hydrogen bond generates an S(5) ring motif. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds into sheets propagating in (-201), which feature R(1) (2)(5), R(2) (2)(8) and R(2) (4)(14) loops.

The title compound, C(9)H(11)N(3)O, was synthesized by the reaction of 4-methyl-benzaldehyde with semicarbazide. The mol-ecule adopts an E configuration about the central C=N double bond and the dihedral angle between the mean planes of the benzene ring and the carboxamide groups is 17.05 (9)°. The hydrazine N atoms are twisted slightly out of the plane of the carboxamide group [C-C-N-N torsion...

The selectivity of the ubiquitin–26 S proteasome system (UPS) for a particular substrate protein relies on the interaction between a ubiquitin-conjugating enzyme (E2, of which a cell contains relatively few) and a ubiquitin–protein ligase (E3, of which there are possibly hundreds). Post-translational modifications of the protein substrate, such as phosphorylation or hydroxylation, are often req...

In the title compound, C(16)H(12)N(2)O, the dihedral angle between the two aromatic ring systems is 68.54 (5)°. The mol-ecular packing is stabilized by intra- and inter-molecular O-H⋯N and intra-molecular C-H⋯N hydrogen-bond inter-actions.

In the title compound, C(12)H(10)N(2)O(2), the dihedral angle between the benzene and furan rings is 52.54 (7)°. In the crystal, inter-molecular N-H⋯O hydrogen bonds and C-H⋯π inter-actions link the mol-ecules.