APO-1 is a 48-Kd transmembrane glycoprotein identical to the Fas antigen and belongs to the nerve growth factor (NGF)/tumor necrosis factor (TNF) receptor family of surface molecules. Cross-linking of APO-1 induces apoptotic cell death in sensitive cells. We show here that APO-1 is an activation molecule on B cells. It was induced/enhanced on dense and buoyant tonsillar B cells, respectively, t...

Bigraphical Reactive Systems (BRSs) have been proposed as a formal metamodel for global ubiquitous computing that encompasses process calculi for mobility, notably the π-calculus and the Mobile Ambients calculus, as well as graphical models for concurrency such as Petri Nets. In this paper we demonstrate that BRSs also allow natural formalizations of programming languages used in practice. We d...

0019-1035/$ see front matter Published by Elsevier doi:10.1016/j.icarus.2011.06.008 ⇑ Corresponding author. Fax: +1 301 286 0440. E-mail address: [email protected] (M.J. Loeffl We report laboratory studies on the 0.8 MeV proton irradiation of ices composed of sulfuric acid (H2SO4), sulfuric acid monohydrate (H2SO4 H2O), and sulfuric acid tetrahydrate (H2SO4 4H2O) between 10 and 180 K. Usin...

Analysis of the Workplace Employment Relations Survey 2004 employee data shows striking differences in levels of overall job satisfaction among occupational groups. The examination is based on the 81 Minor Occupation groupings in UK Standard Occupational Classification 2000 classification. Taking a possible specific occupational effect possibly conditioned by resonance effects, as a theoretical...

BACKGROUND Although serum thyroglobulin (Tg) is an excellent marker for detecting recurrent or persistent differentiated thyroid cancer (DTC), it is unreliable in patients who have positive anti-Tg antibodies. Furthermore, a growing number of patients with DTC have elevated Tg levels but no detectable disease on radioiodine scanning or other imaging studies. The objective of this study was to d...

INTRODUCTION TX-004HR is an investigational, applicator-free, vaginal soft gel capsule containing low-dose solubilized 17β-estradiol. The phase 3, randomized, double-blinded, placebo-controlled, multicenter REJOICE trial has shown TX-004HR to be safe and effective for the treatment of moderate to severe dyspareunia in postmenopausal women with vulvar and vaginal atrophy (VVA). AIM To evaluate...

The global population is aging due to a reduction in youth ful deaths and an extension of the later stages of life. With aging comes a decline in the physiologic functions of vari ous organs and systems. Vascular aging is associated with structural and functional changes of the arterial wall leading to loss of elasticity and compliance. Renal vasculature is not spared as aging is associated wit...

We propose a simple, linear-combination automatic evaluation measure (AEM) to approximate post-editing (PE) effort. Effort is measured both as PE time and as the number of PE operations performed. The ultimate goal is to define an AEM that can be used to optimize machine translation (MT) systems tominimize PE effort, but without having to perform unfeasible repeated PE during optimization. As P...

0019-1035/$ see front matter Published by Elsevier doi:10.1016/j.icarus.2010.09.025 ⇑ Corresponding author. Fax: +1 928 556 7014. E-mail address: [email protected] (C.H. Okubo). The value of slope stability analyses for gaining insight into the geologic conditions that would facilitate the growth of gully alcoves on Mars is demonstrated in Gasa crater. Two-dimensional limit equilibrium methods ar...

0019-1035/$ see front matter 2011 Elsevier Inc. A doi:10.1016/j.icarus.2011.10.004 ⇑ Corresponding author. E-mail address: [email protected] (V.J. Bray). The morphology of impact craters on the icy Galilean satellites differs from craters on rocky bodies. The differences are thought due to the relative weakness of ice and the possible presence of sub-surface water layers. Digital elevation...