As part of the National Institutes of Health Toolbox initiative, we developed a low-cost, easy-to-administer, and time-efficient test of vestibular and visual function. A computerized test of dynamic visual acuity (cDVA) was used to measure the difference in visual acuity between head still and moving in yaw. Participants included 318 individuals, aged 3 to 85 years (301 without and 17 with ves...

BACKGROUND Increased cytoplasmic HuR expression has been noted in several cancer types, where it may contribute to the increased cyclooxygenase-2 (COX-2) expression observed during tumorigenesis and metastasis. METHODS To assess the correlation between COX-2 and HuR in oral squamous cell carcinoma (OSCC), the expression patterns of HuR and COX-2 were assessed via immunohistochemistry analyses...

Luria and Delbrück introduced a very useful and subsequently widely adopted framework for quantitatively understanding the emergence of new cellular lineages. Here, we provide an analytical treatment of the fully stochastic version of the model, enabled by the fact that population sizes at the time of measurement are invariably very large and mutation rates are low. We show that the Lea-Coulson...

A reaction network is a chemical system involving multiple reactions and chemical species. Stochastic models of such networks treat the system as a continuous time Markov chain on the number of molecules of each species with reactions as possible transitions of the chain. In many cases of biological interest some of the chemical species in the network are present in much greater abundance than ...

Abstract Study question What is the effectiveness and safety of various follicular phase ovarian stimulation protocols for intrauterine insemination (IUI) performed any indication? Summary answer Significantly higher LBR/OPR was noted gonadotrophins versus oral agents. Clomiphene+estrogen gonadotrophins+letrozole demonstrated significantly OPR/LBR compared to no stimulation/stimulation with age...

We adopted a game-theoretic approach to studying competition in the software market that is dependent on the network effect, i.e., where the success of the software product is mainly affected by the size of its installed base. The primary goals of our research were: to provide insights into competition between a new entrant with a significant presence in foreign countries and a home-grown incum...

We report Very Large Telescope observations of 11 lensed quasars, designed to measure the redshifts of their lens galaxies. We successfully determined the redshifts for seven systems, five of which were previously unknown. The securely measured redshifts for the lensing galaxies are: HE0047−1756 z = 0.408; PMNJ0134−0931 z = 0.766; HE0230−2130 z = 0.522; HE0435−1223 z = 0.455; SDSS0924+021 z = 0...

OBJECTIVE To determine which particular depressive symptom scales, derived from three scales, predicted poorer prognosis in persons with acute coronary syndrome (ACS). METHODS Hospitalized ACS patients (n=408) completed questionnaires (depression, vital exhaustion). Mokken scaling derived unidimensional scales. Major cardiac events (cardiac mortality, ACS, unplanned revascularization) were as...

Calcium fluoroaluminosilicate glasses (CAS) are used in the formulation of glass ionomer cements for dental applications. However, the cements obtained from CAS glasses were found to be radiolucent. In this study, the influence of substituting Zn, Sr and Mg for Ca of CAS glasses was investigated with respect to the structure and setting characteristics, mechanical properties, and radiopacity of...