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From the Diabetes Research Centre,WHO Collaborating Centre for Research, Education & Training in Diabetes,Chennai-India Correspondence to :Dr. Vijay Viswanathan, Diabetes Research Centre,WHO Collaborating Centre for Research, Education & Training in diabetes 5, Main Road, Royapuram Chennai 600 013.India Efficacy of Glycated Albumin (GA) in Comparison with Glycated Haemoglobin (HbA1c) in Type 2 ...
In this ISR the Proposal Instructions for the NICMOS Science Instrument are described. This report discusses the possible SI configurations, modes, and most of the optional parameters. The optional parameters which support the creation and association of patterns of exposures are discussed in a companion ISR (NICMOS-013).
BACKGROUND AND PURPOSE Sphingosine 1-phosphate (S1P) selectively and potently constricts isolated cerebral arteries, but this response has not been pharmacologically characterized. EXPERIMENTAL APPROACH The receptor subtype(s) involved in S1P-induced cerebrovascular constriction were characterized using genetic (S1P(2) and S1P(3) receptor null mice) and pharmacological tools (phospho-FTY720, ...
Head and neck squamous cell carcinoma (HNSCC) development is closely associated with inflammation. Cyclooxygenase-2 (COX-2) is an important mediator of inflammation. Therefore, celecoxib, a selective inhibitor of COX-2, was hailed as a promising chemopreventive agent for HNSCC. Dose-dependent cardiac toxicity limits long-term use of celecoxib, but it seems likely that this may be diminished by ...
The Poisson sigma model is a widely studied two-dimensional topological field theory. This note shows that boundary conditions for the Poisson sigma model are related to coisotropic submanifolds (a result announced in [math.QA/0309180]) and that the corresponding reduced phase space is a (possibly singular) dual pair between the reduced spaces of the given two coisotropic submanifolds. In addit...
KIR3DL1 is a polymorphic inhibitory receptor that modulates NK cell activity through interacting with HLA-A and HLA-B alleles that carry the Bw4 epitope. Amino acid polymorphisms throughout KIR3DL1 impact receptor surface expression and affinity for HLA. KIR3DL1/S1 encodes inhibitory and activating alleles, but despite high homology with KIR3DL1, the activating receptor KIR3DS1 does not bind th...
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