The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence structure, protecting bacteria from the host immune system and antimicrobial therapy. However, little is known about its responsibility in the interaction of biofilm cells with host tissues. Staphylococcus aureus, a leading cause of biofilm-associated chronic infections, ...

Benzo(a)pyrene (BaP) is highly carcinogenic in rats but is without effect in rabbits when administered s.c. The possibility that BaP-DNA adducts could be responsible for this species difference was investigated by comparing BaP-deoxyribonucleoside adducts formed in dermal fibroblast cultures from Wistar rats and New Zealand rabbits. Treatment with [G-3H]BaP (1.2 microM) for 6, 24, and 48 h prod...

Renal clearance techniques were used to examine the relative contributions of metabolism and renal tubular transport in determining the rates of excretion of benzo(a)pyrene (BaP) and several of its phase I metabolites by southern flounder, Paralichthys lethostigma. Each compound (3H-labeled) was injected at a dose of 2.5 mumole/kg, producing plasma concentrations of 1 to 5 microM. Despite exten...

Our studies found that BRCA1 levels negatively correlate with DNA adducts induced by Benzo(a)pyrene (BaP). Pulse-chase experiments showed that the increase in BaP-induced DNA adducts in BRCA1 knockdown cells may not be associated with BRCA1's function in nucleotide excision repair activity; rather, it may be associated with its function in modulating transcriptional regulation. BRCA1 knockdown ...

The broader autism phenotype (BAP), which refers to the expression of behavioral and cognitive propensities that are milder but qualitatively similar to those defining autism spectrum disorder, can play a crucial role in postpartum depression (PPD). We investigated whether pregnant women’s BAP would increase the risk for PPD, using a representative birth cohort in Japan. Pregnant women were enr...

Biometric Authentication Protocols (BAPs) have increasingly been employed to guarantee reliable access control to places and services. However, it is well-known that biometric traits contain sensitive information of individuals and if compromised could lead to serious security and privacy breaches. Yasuda et al. [23] proposed a distributed privacy-preserving BAP which Abidin et al. [1] have sho...

An efficient embryogenic response (both direct and indirect) of two different varieties of sugarcane (CP 77,400 and BL-4) was obtained in this study. The results demonstrates that fresh inner whorl of leaves and shoot apical meristem of sugarcane were highly amenable to in vitro somatic embryogenesis (both direct and indirect). A combination of 3.0 mg/l 2,4-D with 0.25 mg/l BAP was more potent ...

background & aim: lemon verbena (lippia citriodora h.b.k.) is a richly scented herb and has a long history as a sacred and medicinal plant. select an appropriate medium in tissue culture is a necessity for success experimental: to evaluate the effect of 10 medium of previous researches for lippia micropropagation (1- ms medium supplemented with bap (3 mgl-1) + iba (0.1 mgl-1) + activated ch...

Present report is the first direct evidence of azadirachtin production in androgenic haploid cultures of Azadirachta indica, a woody medicinal tree. Anther cultures at early-late-uninucleate stage of microspores were established on MS medium with BAP (5 μM), 2,4-D (1 μM) and NAA (1 μM) containing 12% sucrose. The calli, induced, were further multiplied on 2,4-D and Kinetin media. Shoots, differ...

in order to find the most effective concentration of 6-banzilamino purine (bap) and cycocel (ccc) on microtuber production of two potato cultivars under tissue culture conditions, a factorial experiment was carried out with randomized compelete design with 4 replications. four levels of bap (0, 5, 10 and 15 mg l-1) and four levels of ccc (0, 250, 500 and 1000 mg l-1) were applied on two potato ...