Restriction-modification (RM) systems represent a minimal and ubiquitous biological system of self/non-self discrimination in prokaryotes [1], which protects hosts from exogenous DNA [2]. The mechanism is based on the balance between methyltransferase (M) and cognate restriction endonuclease (R). M tags endogenous DNA as self by methylating short specific DNA sequences called restriction sites,...

The aim of this study was to determine in humans whether oxidized cholesterol in the diet is absorbed and contributes to the pool of oxidized lipids in circulating lipoproteins. When a meal containing 400 mg cholestan-5alpha,6alpha-epoxy-3beta-ol (alpha-epoxy cholesterol) was fed to six controls and three subjects with Type III hyperlipoproteinemia, alpha-epoxy cholesterol in serum was found in...

SSR or microsatellite markers are proved to be ideal for making genetic maps, assisting selection and studying genetic diversity in germplasm. SSR markers are playing important role to identify gene for salt tolerance that can be helpful for plant breeders to develop new cultivars. The experiment was conducted during the period from July 2009 to November 2010 in the experimental field and Biote...

BACKGROUND AND OBJECTIVE The aim was to evaluate the role of anti-annexin A5 (anti-ANXA5) antibodies as risk factor for recurrent miscarriage (RM) and unexplained fetal loss (UFL). PATIENTS AND METHODS Retrospective, cohort study. SETTING Vall d'Hebron University Hospital. SUBJECTS 122 women, in two groups: STUDY GROUP 54 women with RM/UFL and control group: 68 pregnant without RM/UFL. ...

Abstract We develop a simple analytic model for what happens when an O star (or compact cluster of OB stars) forms in shock compressed layer and carves out approximately circular hole the layer, at waist bipolar H ii Region (H R). The is characterised by three parameters: half-thickness undisturbed $Z_{_{\rm LAYER}}$, mean number-density hydrogen molecules $n_{_{\rm (collective) ionising output...

We present NuSTAR observations of the nearby SN 2023ixf in M101 (d=6.9 Mpc) which provide earliest hard X-ray detection a non-relativistic stellar explosion to date at $\delta t\approx$4-d and t\approx$11-d. The spectra are well described by hot thermal bremsstrahlung continuum with $T>25 \rm{keV}$ shining through thick neutral medium hydrogen column that decreases time (initial $N_{\rm{Hint}}=...

BACKGROUND BDNF is known to induce neuroplasticity and low circulating levels have been related to neuronal loss in older persons. Physical exercise is thought to trigger BDNF-induced neuroplasticity, but conflicting observations have been reported regarding the effects of resistance training on circulating BDNF in the elderly. These conflicting observations might reflect dose-and gender-specif...

In preparation for an experimental study of magnetorotational instability (MRI) in liquid metal, we present non-ideal two-dimensional magnetohydrodynamic simulations of the nonlinear evolution of MRI in the experimental geometry. The simulations adopt initially uniform vertical magnetic fields, conducting radial boundaries, and periodic vertical boundary conditions. No-slip conditions are impos...

We measure the branching fractions and $CP$ asymmetries for singly Cabibbo-suppressed decays $D^{0}\to\pi^{+}\pi^{-}\eta$, $D^{0}\to K^{+}K^{-}\eta$, $D^{0}\to\phi\eta$, using 980 fb$^{-1}$ of data from Belle experiment at KEKB $e^+e^-$ collider. obtain \begin{eqnarray} \mathcal{B}(D^{0}\to\pi^{+}\pi^{-}\eta) & = [1.22\pm 0.02\,({\rm stat})\pm syst})\pm 0.03\,(\mathcal{B}_{\rm ref})]\times 10^{...