BACKGROUND Symptomatic relief is an important treatment goal for patients with COPD. To date, no diary for evaluating respiratory symptoms in clinical trials has been developed and scientifically-validated according to FDA and EMA guidelines. The EXACT - Respiratory Symptoms (E-RS) scale is a patient-reported outcome (PRO) measure designed to address this need. The E-RS utilizes 11 respiratory ...

aus Córdoba (Argentinien) aus Córdoba (Argentinien) aus Córdoba (Argentinien) aus Córdoba (Argentinien) Abstract Abstract Abstract Abstract Hippocampal oscillations and neuronal plasticity are involved in both cognitive functions and pathological processes. In vivo, Sharp wave-ripple (SPW-Rs) consisting of slow field potential transients with superimposed ripples by ca. 200 Hz oscillations are ...

without any doubt, road safety (rs) needs a precise planning in road accident prevention. rs effects on different fields of the life. therefore, response to this need in order to promote the rs as well as to save more lives is the most asset in each country. in the recent years, statistics have been shown that the numbers of mortalities due to road crashes decreased. this shows the true motion ...

Ring sideroblasts (RS) are a distinct morphological feature present in myelodysplastic syndromes (MDS), myelodysplastic/myeloproliferative neoplasms (MDS/MPN) and acute myeloid leukemia (AML). The International Working Group on Morphology of Myelodysplastic Syndrome (IWGM-MDS) defines them as erythroblasts with a minimum of 5 siderotic granules covering at least one third of the circumference o...

The reticulospinal (RS) system is the main descending system transmitting commands from the brain to the spinal cord in the lamprey. It is responsible for initiation of locomotion, steering, and equilibrium control. In the present study, we characterize the commands that are sent by the brain to the spinal cord in intact animals via the reticulospinal pathways during locomotion. We have develop...

a Laboratoire Planétologie et Géodynamique de Nantes, CNRS/Université de Nantes, UMR6112, Nantes, France Department of Geological Sciences, Brown University, 324 Brook St., Providence, RI 02912, USA c Jet Propulsion Laboratory/Caltech Mail Stop 183-301, 4800 Oak Grove Dr., Pasadena, CA 91109, USA d Institut d’Astrophysique Spatiale, CNRS/Université Paris Sud, Orsay, France e Interactions Dynami...

Scott Watson∗ Department of Physics, Brown University, Providence, RI. (Dated: June 5, 2005) Abstract We consider the effect of the ultraviolet (UV) or short wavelength modes on the background of Brane Gas Cosmology. We find that the string matter sources are negligible in the UV and that the evolution is given primarily by the dilaton perturbation. We also find that the linear perturbations ar...

The last few years saw the advent of microblogging platforms, such as Twitter. Such an appeal may be due to platforms’ features allowing to easily and quickly share information in real-time. Microbloggers, while posting microblogs, search for fresh information related to their interests. Finding good results concerning the given subjects needs to consider the characteristics of microblogs, such...