An independent reanalysis of 11 randomized clinical trials shows that oseltamivir treatment reduces the risk of lower respiratory tract complications requiring antibiotic treatment by 28% overall (95% confidence interval [CI], 11%-42%) and by 37% among patients with confirmed influenza infections (95% CI, 18%-52%).

Recent work in supervised learning has shown that a surprisingly simple Bayesian classiier with strong assumptions of independence among features, called naive Bayes, is competitive with state-of-the-art classiiers such as C4.5. This fact raises the question of whether a classiier with less restrictive assumptions can perform even better. In this paper we evaluate approaches for inducing classi...

Here we report the development of a gene-synthesis technology, circular assembly amplification. In this approach, we first constructed exonuclease-resistant circular DNA via simultaneous ligation of oligonucleotides. Exonucleaseand subsequent mismatch cleaving endonuclease–mediated degradation of the resulting ligation mixture eliminated error-rich products, thereby substantially improving gene...

Decision-making about innovative change in high-risk networks is exceptionally difficult because system failure may result in catastrophe. We adopt a historical method to compare the US and Soviet choices in their nuclear attack submarine programs between 1970 and 1996 and to surface their complex political, technological, and operational relations. One program achieved high reliability in the ...

Paulus WE, Zhang M, Strehler E, El Danasouri I, Sterzik K. Influence of acupuncture on the pregnancy rate in patients who undergo assisted reproduction therapy. Fertil Steril 2002;77(4):721-4. Summary The objective of this study was to evaluate the effect of acupuncture on the pregnancy rate in assisted reproduction therapy (ART) by comparing a group of patients receiving acupuncture treatment ...

Introduction Acupuncture is a traditional technique that originated in China more than 3000 years ago, whereby diseases are either controlled or cured by inserting needles in various parts of the body. Until recently the professional community was sceptical about its value, but its use in pain management is now well established. It has also been suggested that acupuncture might improve the immu...

Introduction Myofascial Trigger Points (TrPs) are a common source of musculoskeletal pain presenting in primary care. General practitioners frequently refer these patients to physiotherapy departments for treatment. Identifying TrPs requires training and clinical expertise. Whilst British undergraduate medical and physiotherapy training does not include TrP identification, substantial literatur...

[email protected] The SAR symposium has become a regular feature of the acupuncture research calendar. It started with a small group of people who longed for an open arena in which to discuss acupuncture research without any professional tensions or barriers, and celebrated its tenth anniversary this year. It is a worthy aim to establish a successful society in this under-funded field, and...