Writ/i the technical assistance of Miss Lila Fliegelnian O CCASIONAL REPORTS have presemited cytogenetic data from cases of megaloblastic anemia.ii,uul Although no consistemit cytogenetic abnormalities have yet beeii found, a variety of changes have been described in some cases of pernicious anemia.m’ ’m” The significance of these findings is not clear. This report describes cytogenetic observa...

1. DNA synthesis in the bone marrow and lymphocytes of the vitamin B12-deficient fruit bat (Rosettus Aegyptiacus) has been studied via the deoxyuridine (dU) suppression test. 2. In contrast to vitamin B12 deficiency in man, the dU suppression test was not abnormal in the vitamin B12-deficient bat, and this correlates with the reported finding that the latter does not develop megaloblastic anaem...

To estimate the levels of folic acid, vitamin B12 and their relationship with ferritin in βthalassemia major children. Thirty children with β-thalassemia major in the age group of 4 to 8 years were studied for estimation of serum ferritin, folic acid and vitamin B12 over a period of one year. These tests were determined by means of Immulite 1000 analyzer. The statistical analysis of β-thalassem...

II ECOGNITION of the fully-developed megaloblast in deficiency of vitamm B12 or folic acid is not difficult. In the case of the “intermediate megaloblast” or “megaloblastoid” cell, however, identification of megaloblastic changes often becomes more difficult, and more subjective.1 The present study attempts to reduce this subjectivity by demonstrating a unique clockface chromatin pattern along ...

BACKGROUND Hyperthyroidism, the most common endocrine disorder in cats, has been associated with low serum cobalamin concentrations. Whether this is a functional cobalamin deficiency of clinical importance has not been assessed. HYPOTHESIS/OBJECTIVES Cats with hyperthyroidism experience a functional cobalamin deficiency which correlates with their clinical catabolic state and is reversible wi...

II ECOGNITION of the fully-developed megaloblast in deficiency of vitamm B12 or folic acid is not difficult. In the case of the “intermediate megaloblast” or “megaloblastoid” cell, however, identification of megaloblastic changes often becomes more difficult, and more subjective.1 The present study attempts to reduce this subjectivity by demonstrating a unique clockface chromatin pattern along ...

II ECOGNITION of the fully-developed megaloblast in deficiency of vitamm B12 or folic acid is not difficult. In the case of the “intermediate megaloblast” or “megaloblastoid” cell, however, identification of megaloblastic changes often becomes more difficult, and more subjective.1 The present study attempts to reduce this subjectivity by demonstrating a unique clockface chromatin pattern along ...