osteoarthritis (oa) a common disease of aged population and one of the leading causes of disability. incidence of knee oa is rising by increasing average age of general population. age, weight, trauma to joint due to repetiting movements in particular squatting and kneeling are common risk factors of knee oa. several factors including cytokines, leptin, and mechanical forces are pathogenic fact...

osteoarthritis is the most common joint disease.the main pathologic manifestation of disease is local destruction of cartilage in diarthrodial joint. new bone formation in marginal surface of the joint is a sign progressive disease. many systemic and local factors are introduced in initiate and progression of osteoarthritis include: age, sex, weight, race, genetic background, bone densitometry,...

objectives thereby the prevalence, distribution characteristics and correlative factors of oa in mongolian middle-aged and senior residents in the inner mongolia autonomous region were investigated in this study. materials and methods rural and urban residents in hohhot, baotou and erdos were selected using stratified, multi-stage and cluster random sampling. 2000 residents aging over 45 filled...

BACKGROUND Fractures of the shaft of the tibia often heal with some angulation. Although there is biomechanical evidence that such angulation alters load transmission through the joints of the lower limb, it is not clear whether it can eventually lead to osteoarthritis. METHODS One hundred and sixty-four individuals who had sustained a tibial shaft fracture were assessed in a research clinic ...

Hyaluronic acid (HA) and platelet-rich plasma (PRP) are two non-operative treatment options for patients with early hip osteoarthritis (OA). The purpose of this study was to compare the efficacy intra-articular injections HA PRP in OA. Patients presenting a preservation surgeon signs OA were randomized or PRP. Each patient received 3 at 1-week intervals either followed minimum 12-months. primar...

26 patients with osteoarthritis of the knees were randomly divided into 2 groups of 13 each with patients of similar ages, sex distribution and duration and severity of disease. All were treated with daily baths at 34-35 degrees C for 20 min. containing Dead Sea bath salts (Group I) or sodium chloride (Group II). The study was double-blind and of 2 weeks duration. Patients were evaluated by a r...

From a search of MRI reports on knees, 20 patients were identified with evidence of early anteromedial osteoarthritis without any erosion of bone and a control group of patients had an acute rupture of the anterior cruciate ligament. The angle formed between the extension and flexion facets of the tibia, which is known as the extension facet angle, was measured on a sagittal image at the middle...

BACKGROUND Recent studies show that enzymatically hydrolysed collagen, the collagen peptide, is absorbed and distributed to joint tissues and has analgesic and anti-inflammatory properties. A double-blind, placebo-controlled, randomised trial with collagen peptides isolated from pork skin (PCP) and bovine bone (BCP) sources was carried out to study the effectiveness of orally supplemented colla...

A retrospective cohort study of important musculoskeletal conditions of Thoroughbred racehorses was conducted using health records generated over a 15 year period (n=5062, 1296 sires). The prevalence of each condition in the study population was: fracture, 13%; osteoarthritis, 10%; suspensory ligament injury, 10%; and tendon injury, 19%. Linear and logistic sire and animal regression models wer...