The paper presents a missive from the Grand Duke of Moscow Ivan III declaring war to Lithuania Aleksander Jagiellończyk on June 24th, 1500. missive, so far unaccounted in scientific publications, survives Middle Low German translation kept archive Hanseatic City Lübeck. declaration is motivated by alleged injustices done III, his subjects and daughter Elena Ivanovna, who was Aleksander’s wife. ...

Background It is unclear whether topical (intra-articular) or intravenous TXA reduces blood loss in minimally invasive TKA patients receiving a direct oral anticoagulant for thromboprophylaxis. This study is to investigate whether TXA given intravenously or intra-articularly is effective in reducing blood loss in minimally invasive TKA patients using rivaroxaban for thromboprophylaxis. Method...

Phytohormone salicylic acid (SA) plays an important role in regulating various physiological and biochemical processes. Our previous study identified several protein kinases responsive to SA, suggesting that phosphorylation events play an important role in the plant response to SA. In this study, we characterized the phosphoproteome of maize in response to SA using isotope tags for relative and...

Title: 1 ATP and the purine type 2 X7 receptor affect sleep 2 Authors and author addresses: 3 James M. Krueger, Ping Taishi, Alok De, Christopher J. Davis, Bradley D. 4 Winters, James Clinton, Éva Szentirmai , Mark R. Zielinski 5 Sleep and Performance Research Center, Programs in Neuroscience, and 6 College of Veterinary Medicine, Washington State University, Pullman, 7 WA, USA 99164-6520 8 2 C...

Genes encoding the opioid receptors (OPRM1, OPRD1 and OPRK1) are obvious candidates for involvement in risk for heroin dependence. Prior association studies commonly had samples of modest size, included limited single nucleotide polymorphism (SNP) coverage of these genes and yielded inconsistent results. Participants for the current investigation included 1459 heroin-dependent cases ascertained...

The glycoprotein gp210 is located in the "pore membrane," a specialized domain of the nuclear envelope to which the nuclear pore complex (NPC) is anchored. gp210 contains a large cisternal domain, a single transmembrane segment (TM), and a COOH-terminal, 58-amino acid residue cytoplasmic tail (CT) (Wozniak, R. W., E. Bartnik, and G. Blobel. 1989. J. Cell Biol. 108:2083-2092; Greber, U. F., A. S...

The foundation of surgical robotics is in the development of the robotic arm. This is a thorough review of the literature on the nature and development of this device with emphasis on surgical applications. We have reviewed the published literature and classified robotic arms by their application: show, industrial application, medical application, etc. There is a definite trend in the manufactu...

STUDY OBJECTIVE The aim was to assess the geographical variation in low back pain and associated disability in Britain. DESIGN This was a cross sectional survey with information collected by postal questionnaire. SETTING General practices in seven British towns and one rural district. SUBJECTS 1172 men and 1495 women aged 20-59 years were selected from the age-sex registers of 136 general...

We extract 1495 speech features from 2 subjectively evaluated text-to-speech (TTS) databases. These features are extracted from pitch, loudness, MFCCs, spectrals, formants, and intensity. The speech material is synthesized using up to 15 different TTS systems, some of them with up to 8 different voices. We develop quality predictors for TTS signals following two different approaches to handle t...