Adenosine is an important inhibitory neuromodulator in the CNS, yet the sources of extracellular adenosine have yet to be well characterized. In this study we show that beta-adrenergic stimulation of cortical cultures results in the extracellular accumulation of cAMP as well as adenosine, and that the extracellular adenosine derives from extracellular cAMP. The concentration dependence of isopr...

Introduction. The article publishes one of the last letters submitted by Khan Ayuka Kalmyks to Russian Emperor Peter Great. Goals. work aims at introducing newly discovered correspondence dealing with Russian-Kalmyk relations in first quarter 18th century. Materials. document analyzed is contained Collection 119 (‘Kalmyk Affairs’) Imperial Russia’s Foreign Policy Archive that houses quite a num...

In this study we used dendrochronology to reconstruct the history of eastern spruce budworm (Choristoneura fumiferana (Clem.)) outbreaks over the last 450 years in the Bas-Saint-Laurent region of southeastern Quebec. In total, 260 tree cores were sampled from 204 beams in seven historic buildings and 12 trees in a virgin forest stand. Eight previously documented outbreaks (1975–1992, 1947–1958,...

Goldberg (1972) has postulated the presence of specific dopamine receptors in renal and mnesenteric vascular smooth muscle. There is also some evidence that such receptors may also play a role in the coronary dilator effects of dopamine (Schuelke, Mark, Schmid & Eckstein, 1971; Toda & Goldberg, 1975). We have examined this possibility by comparing the effects of dopamine, dobutamine, noradrenal...

Micropressure ejection of serotonin (5-hydroxytryptamine, 5-HT) produced excitatory responses in the L14 ink motor neurons of Aplysia that depended on the site of application. Ejection of 5-HT onto the cell body produced a slow response that showed variability in voltage sensitivity between preparations. In contrast, ejection of 5-HT onto the neuropil underneath the cell body produced a respons...

The achievements of Russian science and education form a reliable basis for the innovative development modern economy. It is quite natural, therefore, that there an interest in origins origin Russia. In preparing this article, author relied on materials books written by him about such outstanding scientists as Leonard Euler, Mikhail Lomonosov, Dmitry Mendeleev, who forever inscribed their names...