The prognostic value of an interim fluorine-18-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) for diffuse large B-cell lymphoma (DLBCL) has been assessed by different groups. However, studies have suggested that the use of rituximab could limit the predictive value of interim (18)F-FDG PET for DLBCL. To clarify the prognostic value of interim (18)F-FDG PET in DLBCL patients tre...

UNLABELLED By conventional imaging modalities, the discrimination between acute and chronic aortic dissection (AD) for surgical risk evaluation is not possible. However, acute and chronic stable AD potentially may be distinguished by detection of reparatory hypermetabolism in the lacerated aortic wall of acute AD using (18)F-FDG PET/CT. In this study, we analyzed the (18)F-FDG uptake in the aor...

UNLABELLED 3'-Deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) is a recently developed PET tracer to image tumor cell proliferation. We characterized (18)F-FLT PET of brain gliomas and compared (18)F-FLT with (18)F-FDG PET in side-by-side studies of the same patients. METHODS Twenty-five patients with newly diagnosed or previously treated glioma underwent PET with (18)F-FLT and (18)F-FDG on consecu...

AbstractPurpose We aimed to compare the diagnostic performance of PET/CT imaging performed with 68Ga-DOTA-FAPI and 18FDG in detection liver metastases patients gastrointestinal system (GIS) cancer. Methods A total 31 who underwent 18F-FDG examinations diagnosed GIS cancer (15 colorectal, 9 pancreas, 4 stomach 3 other cancers) were incl...

UNLABELLED Cardiac PET using (18)F-FDG under fasting conditions (fasting (18)F-FDG PET) is a promising technique for identification of cardiac sarcoidosis and assessment of disease activity. The aim of this study was to investigate the usefulness of fasting (18)F-FDG PET in detecting inflammatory lesions of cardiac sarcoidosis from a pathophysiologic standpoint. METHODS Twenty-two patients wi...

UNLABELLED The prognosis of patients with locally advanced breast cancer (LABC) remains poor. We prospectively investigated the impact of (18)F-FDG PET/CT at initial staging in this clinical setting and compared PET/CT performance with that of conventional distant work-up. METHODS During 60 mo, consecutive patients with LABC (clinical T4 or N2-N3 disease) underwent (18)F-FDG PET/CT. The yield...

UNLABELLED For (18)F-FDG PET to be widely used to monitor atherosclerosis progression and therapeutic response, it is crucial to better understand how macrophage glucose metabolism is influenced by the atherosclerotic microenvironment and to elucidate the molecular mechanisms of this response. Oxidized low-density lipoprotein (oxLDL) is a key player in atherosclerotic inflammation that promotes...

a 60-year-old patient with testicular seminoma was referred for f-18 fdg pet/ct study to evaluate recurrence. in addition to hypermetabolic cervical, mediastinal and hilar lymph node tumoral metastases, segmental intense fdg uptake along the lumbar spinal cord suggestive of tumoral metastasis was noted which quite an unusual presentation is.  at the time of pet study the patient was symptomless...

background: in the era of well-developed site-specific treatment strategies in cancer, identification of occult primary is of paramount importance in cup patients. furthermore, exact determination of the extent of the disease may help in optimizing treatment planning. the aim of the present study was to investigate additional value of f-18 fdg pet/ct in patients with cancer of unknown primary (...

BACKGROUND This study investigated whether changing a tumor's oxygenation would alter tumor metabolism, and thus uptake of (18)F-FDG (fluorine-18 deoxyglucose), a marker for glucose metabolism using positron emission tomography (PET). RESULTS Tumor-bearing mice (squamous cell carcinoma) maintained at 37 degrees C were studied while breathing either normal air or carbogen (95% O(2), 5% CO2), k...