Purpose: To determine the value of diffusion-weighted MRI (DWI-MRI) for treatment response assessment in 2-[18F]fluoro2-deoxy-D-glucose (FDG)–avid lymphoma. Experimental Design: Patients with FDG-avid Hodgkin (HL) or non-Hodgkin lymphoma (NHL) at pretherapeutic 18F-FDGPET/CT, who had also undergone pretherapeutic whole-body DWI-MRI, were included in this prospective study. Depending on the hist...

We present the case of an 11 year-old Caucasian girl who presented chest pain of 12 weeks evolution, with no other symptoms and a negative physical examination. Lactate dehydrogenase levels were increased to 797 U/l, whereas beta-2-microglobulin (BM2) levels were normal. The thoracic CT showed a bulky mediastinal mass that occupied the pretracheal, paratracheal and right prevascular regions. Th...

To compare the diagnostic performance of 18F-FDG PET, 11C-FMZ PET, and 11C-FMZ BP imaging for the evaluation of patients with intractable partial epilepsy whose MRI findings are normal by using statistical imaging analysis. Ten patients underwent comprehensive presurgical evaluation, including PET studies, to assess the epileptic foci. The extent of cortical resection was based on the results o...

conclusion of the asymptomatic patients investigated, 58% showed focal enhanced periprosthetic glucose metabolism. this finding should be taken into consideration as a more probable unspecific metabolic pattern for correct interpretation of 18f-fdg-pet studies in patients with suspected septic loosening of the hip prosthesis. results fourteen hip prostheses in 12 patients were visually analyzed...

in this case we report the detection of lymph node metastases in a 52 years old patient with mycosis fungoides utilising 18f- fdg-pet/ct which led to a change in the management of the patient.

OBJECTIVES This study assessed 5 frequently applied arterial 18fluorodeoxyglucose (18F-FDG) uptake metrics in healthy control subjects, those with risk factors and patients with cardiovascular disease (CVD), to derive uptake thresholds in each subject group. Additionally, we tested the reproducibility of these measures and produced recommended sample sizes for interventional drug studies. BAC...

METHODS Thirty patients with proven colorectal cancer prospectively underwent integrated 18F-FDG PET/DCE-CT to assess the metabolic-flow phenotype. Both CT blood flow parametric maps and PET images were analyzed. Correlations between PET heterogeneity and perfusion CT were assessed by Spearman's rank correlation analysis. RESULTS Blood flow visualization provided by DCE-CT images was signific...

To our knowledge, no study investigating the usefulness of cardiac PET for detection of myocardial involvement of sarcoidosis is available. We investigated whether N-NH3/F-FDG PET could identify cardiac involvement in patients with sarcoidosis. Methods: Seventeen patients with cardiac sarcoidosis underwent cardiac N-NH3/F-FDG PET under fasting condition. Systemic sarcoidosis was diagnosed by hi...

Objective(s): Use of a positron emission tomography (PET)/single-photonemission computed tomography (SPECT) system facilitates the simultaneousacquisition of images with fluorine-18 fluorodeoxyglucose (18F-FDG) andtechnetium (99mTc)-tetrofosmin. However, 18F has a short half-life, and 511keV Compton-scattered photons are detected in the 99mTc energy window.Therefore, in this study, we aimed to ...

Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F) fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker for enhanced intracellular glycolysis and metabolic function, one of the newer tracers, (18F)-3’-fluoro-3’ deoxy...