BACKGROUND Oxycodone/naloxone (OXN PR) is a prolonged-release formulation containing oxycodone and naloxone in a 2:1 ratio. This study aimed to evaluate the tolerability and efficacy of doses up to OXN160/80 mg PR compared with oxycodone prolonged-release formulation (OxyPR) in a randomised controlled trial. METHODS Two hundred and forty-three patients were randomised to treatment with OXN PR...

OBJECTIVE To investigate whether fatigue induced by an intermittent motor task in patients with cancer-related fatigue (CRF) is more central or peripheral. METHODS Ten patients with CRF who were off chemo and radiation therapies and 14 age-matched healthy controls were enrolled. Participants completed a Brief Fatigue Inventory (BFI) and performed a fatigue task consisting of intermittent elbo...

The aim of this study was to determine whether personality traits, interpersonal conflict resolution strategies, and coping skills differ from one another according the generations (X, Y, Z). Hence, how Z) differentiate approaches, explored. sample consisted 433 participants (257 female 176 male) which are composed Generation X (n = 141), Y 165), Z 127). data obtained by Demographic Information...

The aim of this study is to evaluate the convergent and operational validity a modified Latvian personality inventory (LPA-3, Perepjolkina, 2014) with multidimensional forced-choice answer format (LMFI). Using three samples, LMFI was conducted. Convergent evaluated by examining relations between on one side Big Five Inventory (BFI) Machiavellianism scale other. Operational assessments subjectiv...

We observe the acoustic velocity oscillations in and near active region NOAA 10960 on 8 June, 2007 using observations from the IBIS instrument at the Dunn Solar Telescope at NSO/Sacramento Peak and simultaneous Hinode BFI/SP data. Inversions were performed on the spectropolarimetric datasets in order to get magnetic field information for the AR. A time series of Doppler maps from line bisectors...

In a peer-to-peer system of interacting Byzantine-fault-tolerant replicated-state-machine groups, as system scale increases, so does the probability that a group will manifest a fault. If no steps are taken to prevent faults from spreading among groups, a single fault can result in total system failure. To address this problem, we introduce Byzantine Fault Isolation (BFI), a technique that enab...

Background: The period of Covid 19 epidemic effect not only illness people but also human lives. A lot People, participating some activities in gym center from Kayseri. Some restraint during the covid by ministry interior was affected who went to fitness center. This situation Body Weight, Mass Index, Fat Index unfavorable. Aim: purpose this study determine physical changes participants activel...