نتایج جستجو برای: 203 ق

تعداد نتایج: 11911  

2014
LIFENG MIAO XIANZE XIONG YIXIN LIN YAO CHENG JIONG LU JIE ZHANG NANSHENG CHENG

Pancreatic cancer is one of the most lethal malignant diseases with the poorest prognosis and is the fourth leading cause of tumor-associated mortality in the industrialized world. microRNAs (miRNAs or miRs) are small noncoding RNAs of approximately 22 nucleotides long that are able to function as oncogenes or tumor suppressors in human cancer. In our study, overexpression of miR-203 in Panc-1 ...

2017
T. Peter Kingham Hoang C.B. Nguyen Jian Zheng Ioannis T. Konstantinidis Eran Sadot Jinru Shia Deborah Kuk Steven Zhang Leonard Saltz Michael I. D’Angelica William R. Jarnagin Hani Goodarzi Sohail F. Tavazoie

BACKGROUND Resection of colorectal liver metastasis (CRLM) can be curative. Predicting which patients may benefit from resection, however, remains challenging. Some microRNAs (miRNAs) become deregulated in cancers and contribute to cancer progression. We hypothesized that miRNA expression can serve as a prognostic marker of survival after CRLM resection. RESULTS MiR-203 was significantly over...

Journal: :Language literacy 2023

The study analyses the phonological interference of phoneme pronunciation [q] by Sundanese and Javanese speakers compared with Arabic speakers. researchers used a descriptive comparative qualitative method. listened, took notes, documented voice recordings male students from ethnic groups when reading Qur'an to collect research data analyse it using Praat software version 6.2.13. From results r...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2013
Francesco Potì Fabio Gualtieri Sandro Sacchi Gabriele Weißen-Plenz Georg Varga Martin Brodde Christian Weber Manuela Simoni Jerzy-Roch Nofer

OBJECTIVE Sphingosine 1-phosphate (S1P) partly accounts for antiatherogenic properties of high-density lipoproteins. We previously demonstrated that FTY720, a synthetic S1P analog targeting all S1P receptors but S1P receptor type 2, inhibits murine atherosclerosis. Here, we addressed the identity of S1P receptor mediating atheroprotective effects of S1P. APPROACH AND RESULTS Low-density lipop...

Journal: :International journal of clinical and experimental pathology 2015
Liang Shi Qinghong Xin Ruonan Chai Lei Liu Zhuang Ma

MiRNA is a group of powerful short non-coding RNAs that suppress the expression of protein coding genes by targeting to the 3'UTRs of mRNAs. Some researchers have detected the miRNAs expression profile in tissue and blood samples of chronic obstructive pulmonary disease (COPD) patients recently. Several disturbed miRNAs were found to be related to COPD; however, the mechanisms were still well u...

2016
Xiuli Yan Shengliang Zhu Hui Zhang

Background and Aim. MicroRNAs (miRNAs) have been implicated in the pathophysiology of numerous human diseases including gastroesophageal reflux disease (GERD). The objective of this study was to investigate the miRNA expression of exfoliated cells of the tongue in patients with GERD versus healthy controls (Ctrls). Methods. Using quantitative reverse-transcription PCR (qRT-PCR), expression leve...

2016
Yi Zhang Shu-yan Zhou Hai-zhao Yan Dan-dan Xu Hai-xuan Chen Xiao-yan Wang Xiao Wang Yu-ting Liu Li Zhang Sheng Wang Peng-jun Zhou Wu-yu Fu Bi-bo Ruan Dong-lei Ma Ying Wang Qiu-ying Liu Zhe Ren Zhong Liu Rong Zhang Yi-fei Wang

Drug resistance is one of the leading causes of failed cancer therapy in the treatment of acute myeloid leukemia. Although the mechanisms of resistance are poorly understood, they may be related to the presence of leukemia stem cells (LSCs). Down-regulation of the miR-203 reportedly contributes to oncogenesis and chemo-resistance in multiple cancers. We found that miR-203 expression was down-re...

2011
R. Sudirman

Problem statement: The study of Malaysian Arabic phoneme is rarely found which make the references work difficult. Specific guideline on Malaysian subject is not found even though a lot of acoustic and phonetics research has been done on other languages such as English, French and Chinese. Approach: This study discussed about the correct and simplest way of Arabic phonemes pronunciation in Mala...

2009
Sahar A. Alshalchi Layla K. Mahdi Muna Sabar

C-reactive protein (CRP) is an acute phase reactant the concentration of which increases significantly following tissue injury or inflammation. It is present in the albumin fraction of the serum of patients and is antigenic upon injection into rabbits. We report here the development of a local latex reagent coated with rabbit anti-CRP. For this purpose CRP was isolated from pooled sera of patie...

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