Abstract Medulloblastomas (MBs) are the most common malignant childhood brain tumors, yet origin of aggressive subgroup-3 form remains elusive, impeding development effective targeted treatment strategies. Previous cell-type analyses mouse cerebella or human counterparts from frozen tissue nuclei have not fully defined compositional heterogeneity MBs. Here, we undertook an unprecedented single-...

Background:  Cotton seed is one of the main sources of protein in animal feeds, containing gossypol, which has been shown to have toxic effects. Results reported by various studies also indicate the anti-cancer effects of gossypol on various cell types. However, its toxic effects on human and animal cells have not been fully established. This study was planned to investigate, for the first time...

The title compound, C(16)H(14)Cl(2)N(4), is isomorphous with 2,9-dimethyl-6H,13H-5:12,7:14-dimethano-dibenzo[d,i]-[1,3,6,8]tetra-azecine [Rivera et al. (2009 ▶). Acta Cryst. E65, o2553] and has twofold symmetry, with two carbon atoms located on a twofold axis. Only van der Waals forces occur between molecules in the crystal. In the isomorphous compound the crystal structure is stabilized by wea...

1.1 MYSTIFICATION = Distortions of perceptions of reality that mask/obscure that reality. Ideological practices produce human beings as social subjects by transforming “lived experiences” into subjectivity. Mystification concerns the ways in which cognitive understandings of “what exists” are formed out of our lived experiences, formed in such a way that they distort and mask the way the social...