BACKGROUND Both stenting and the glycoprotein IIb/IIIa inhibitor abciximab improve outcomes for patients undergoing primary angioplasty for acute myocardial infarction (AMI). However, the cost-effectiveness of these strategies is unknown. METHODS AND RESULTS We performed a prospective cost-utility analysis among US participants in the CADILLAC trial. Patients with AMI (n=1703) were randomized...

We have developed a general equilibrium model that belongs to the class of real business cycle models small open economy exporting natural resources, which allows us take into account impact investments in infrastructure projects. The was calibrated perform deterministic simulation project new railway construction and associated enterprises for extraction primary processing resources Siberia Fa...

BACKGROUND Rapid scale-up of antiretroviral therapy (ART) is a worldwide priority, and ambitious targets for numbers on ART have been set. Antenatal clinics (ANCs) and tuberculosis (TB) clinics have been targeted as entry points into HIV care. METHODS We developed a conditional probability model to evaluate the effects of ANC and TB clinic populations on ART program enrollment. RESULTS To s...

BACKGROUND The National Lung Screening Trial (NLST) results indicate that computed tomography (CT) lung cancer screening for current and former smokers with three annual screens can be cost-effective in a trial setting. However, the cost-effectiveness in a population-based setting with >3 screening rounds is uncertain. Therefore, the objective of this study was to estimate the cost-effectivenes...

INTRODUCTION Excellent treatment outcomes with long-term durability and few adverse effects are expectations of treatments for chronic conditions. The long-term cost effectiveness of newer treatments for benign prostatic hyperplasia (BPH), including high-energy transurethral microwave thermotherapy (TUMT) and combination pharmaceutical therapy, has not been sufficiently studied against existing...

OBJECTIVES The objective of this study was to determine the financial incentives that companies have to treat HIV-infected employees, in a health care services company in Kampala, Uganda. DESIGN Cost-benefit analysis from the company's perspective of three interventions to treat HIV-infected employees. METHODS The costs and benefits of each intervention were compared with no intervention an...