BACKGROUND In 2002, the euthanasia act came into effect in the Netherlands, which was followed by a slight decrease in the euthanasia frequency. We assessed frequency and characteristics of euthanasia, physician-assisted suicide, and other end-of-life practices in 2010, and assessed trends since 1990. METHODS In 1990, 1995, 2001, 2005, and 2010 we did nationwide studies of a stratified sample...

为了改善生态调度效果,提高生态调度实践成功率,采用医学领域适用性广、准确性高、直观性强的受试者工作特征曲线法(receiver operating characteristic, ROC),以三峡水库为例,提出了一套基于生物水文响应模型的刺激四大家鱼繁殖生态调度目标量化方法,包括涨水事件界定及生态水文指标选择、鱼类自然繁殖事件及有效繁殖响应界定、生物-水文响应模型构建与多指标判别优选等多个环节。运用三峡水库运行后2013—2019年(除2016年)6年47场次宜昌江段的涨水事件和24次四大家鱼有效繁殖响应的实际观测数据构建模型并量化三峡水库生态调度目标。结果表明:(1)依据初始流量Q0、洪峰流量Qpeak、流量总增长量Qsum和流量日增长率dQ这4个指标所建立的单指标生物-水文响应模型具有较好判别四大家鱼自然繁殖对水文...

Extrapolation of results from empirical studies of natural or anthropogenic perturbations are a useful tool in estimating potential effects of future impacts, For 5 years we studied the direct effects of a major oil spill on fringing red mangroves (Rhizophora mangle) and the organisms that live attached to their submerged prop roots, Based on these data, we here estimate the effects of this oil...

Catheter ablation procedures are performed in 5-10% of patients suffering from atrial fibrillation (AF). 3 While the main reason for undertaking AF ablation is because the patient is suffering from symptomatic AF, those who undergo AF ablation are younger and ‘generally healthier’ than patients who do not undergo ablation treatment, 6 as reflected by lower stroke risk scores, but also driven by...

This paper proposes an efficient pipelined architecture of elliptic curve scalar multiplication (ECSM) over GF(2 m ). The architecture uses a bit-parallel finite field (FF) multiplier accumulator (MAC) based on the Karatsuba–Ofman algorithm. The Montgomery ladder algorithm is modified for better sharing of execution paths. The data path in the architecture is well designed, so that the critical...

In this paper we develop a model in which up to 30 employee stock options issued by the same firm can be valued simultaneously and demonstrate that standard methods of valuation can result in under-valuation, especially for long-dated options and for options where the proportion of outstanding options is large relative to the number of outstanding shares of equity. We also develop a version of ...

The concept of myocardial ischemic ‘preconditioning’ protection; (ii) summarize, for each of these multiple (PC) has been with us since 1986 [1]. A tremendous body scenarios, the potential benefits that might be achieved in of research over the last 15 years has documented this the implementation of PC as a therapeutic strategy; (iii) phenomenon in virtually every species tested, with both an o...

BACKGROUND Adolescent females send and receive more text messages than any others, with an average of 4050 texts a month. Despite this technological inroad among adolescents, few researchers are utilizing text messaging technology to collect real time, contextualized data. Temporal variables (ie, mood) collected regularly over a period of time could yield useful insights, particularly for evalu...